Publications

Prevention of Depression in At-Risk Adolescents: Longer-term Effects Beardslee WR, Brent DA, Weersing VR, Clarke GN, Porta G, Hollon SD, Gladstone TRG, Gallop R, Lynch FL, Iyengar S, DeBar L, Garber J Depression is a major public health problem with first onset often occurring during adolescence and affecting close to a quarter of all adults during their lifetime. Children of depressed parents are at high risk for...

Differences in Acute Response to Alcohol Between African Americans and European AmericansPedersen SL and McCarthy DM While previous studies have pointed to response to alcohol as an endophenotype for alcohol use disorders, limited work has examined response to alcohol in African Americans, and prior research has not been conducted to directly compare the acute alcohol response of African Americans to European...

Psychiatric Characteristics of Homicide DefendantsMartone CA, Mulvey MD, Yang S, Nemoianu A, Shugarman R, and Soliman L. Most studies on mental disorder rates among perpetrators have been conducted in Europe, and have shown a higher occurrence of disorders in homicide offenders than in the general population. However, the applicability of these results to the US population is questionable. In addition, the results...

A Novel Approach for Developing and Interpreting Treatment Moderator Profiles in Randomized Clinical TrialsWallace ML, Frank E, and Kraemer HC Mental health practitioners need better methods for personalizing treatment selection for individual patients. In the treatment of depression, for example, initial treatments may succeed as infrequently as one-third of the time, with additional treatments increasing the...

Cocaine-Induced Membrane Adaptation in the Central Nucleus of Amygdala Chen B, Ma Y-Y, Wang Y, Wang X, Schülter OM, Dong Y, and Huang YH After the initial pleasurable feelings subside, chronic drug users typically experience a withdrawal-related negative emotional state that includes unhappiness, stress, anxiety, and depression. The central nucleus of the amygdala (CeA) is a brain area that is involved in the...

Trajectories of Depressive Symptoms and Suicidality Among Heterosexual and Sexual Minority YouthMarshal MP, Dermody SS, Cheong J, Burton CM, Friedman MS, Aranda F and Hughes TL Although studies have shown that sexual minority youth (adolescents who report a same-sex romantic or sexual orientation) report higher rates of depression and suicidality than do heterosexual youth, it was unclear whether these disparities...