Publications

Incorporating Dimensions into the Classification of Eating Disorders: Three Models and Their Implications for Research and Clinical PracticeWildes JE and Marcus MD Integration of dimensional approaches is a growing trend within the mental health field, expanding upon the traditional approach of classifying patients strictly by categories. The DSM-5 Task Force and the National Institute of Mental Health have...

fNIRS evidence of prefrontal regulation of frustration in early childhoodPerlman SB, Luna B, Hein TC, Huppert TJ Frustration is a common experience in early childhood, yet its neural mechanisms have rarely been studied. A project by Dr. Susan Perlman and her colleagues investigated the neural substrate of frustration in children aged 3 to 5 years old. Children in the study were assessed using functional near...

Identifying Prolonged Grief Reactions in Children: Dimensional and Diagnostic ApproachesMelhem NM, Porta G, Payne MW, and Brent DA When children and adolescents experience the sudden death of a parent, they are at risk for prolonged grief reactions, also known as complicated grief. Identifying such reactions is important because children with this condition are at increased risk for depression and for decline in...

White Matter Microstructure, Alcohol Exposure, and Familial Risk for Alcohol Dependence Hill SY, Terwilliger R, McDermott M Numerous investigations that focus on individuals with chronic alcohol dependence show that long-term consumption of alcohol is associated with both brain morphological and neurocognitive changes. There is an intriguing possibility that some of the observed variation in structural and...

Parvalbumin-Containing Chandelier and Basket Cell Axon Terminals have Distinctive Modes of Maturation in Monkey Prefrontal Cortex Fish KN, Hoftman G, Sheikh W, Kitchens M, and Lewis DA Schizophrenia is a neurodevelopmental disorder that afflicts approximately 1.0% of the world?s population. While positive symptoms (i.e. psychotic symptoms) are most commonly associated with the illness, cognitive deficits are the...

Fronto-limbic Function in Unaffected Offspring at Familial Risk for Bipolar Disorder During an Emotional Working Memory Paradigm Ladouceur CD, Diwadkar VA, White R, Bass J, Birmaher B, Axelson DA, Phillips ML. Evidence from neuroimaging studies indicate that individuals with bipolar disorder exhibit altered functioning of the brain?s fronto-limbic systems implicated in voluntary emotion regulation. Few studies...