Publications

Evening-Type Military Veterans Report Worse Lifetime Posttraumatic Stress Symptoms and Greater Brainstem Activity across Wakefulness and REM SleepHasler BP, Insana SP, James JA, Germain A Individual preferences in sleep-wake timing, or morningness-eveningness, colloquially referred to as being an ?early bird? or a ?night owl,? can be associated with mental and physical health outcomes. Various studies have linked...

Cholinergic modulation of neuronal excitability and recurrent excitation-inhibition in prefrontal cortex circuits: implications for gamma oscillations Pafundo DE, Miyamae T, Lewis DA and Gonzalez-Burgos G Cognitive functions such as working memory, the ability to hold and use small amounts of information in one?s mind for a short period of time, depend on the rhythmic activity of networks of neurons known as gamma...

Mild Cognitive Impairment: Incidence and Vascular Risk Factors in a Population-Based Cohort Ganguli M, Fu B, Snitz BE, Hughes TF, Chang CCH Mild cognitive impairment is a cognitive state intermediate between normal cognitive aging and dementia. In a recent study published in the journal Neurology, Dr. Mary Ganguli and her colleagues examined the incidence of mild cognitive impairment in previously normal older...

Altered Parvalbumin Basket Cell Inputs in the Dorsolateral Prefrontal Cortex of Schizophrenia Subjects Glausier JR, Fish KN, and Lewis DA Although psychosis is the most striking feature of schizophrenia, cognitive dysfunction is now recognized as a core feature of the illness. Indeed, cognitive ability in this patient population is the best predictor of employment, social integration, and even relapse. However...

Reward Signals, Attempted Suicide, and Impulsivity in Late-Life Depression Dombrovski AY, Szanto K, Clark L, Reynolds CF, and Siegle GJ Suicidal behavior is heterogeneous and we know little about the many pathways that lead to it. In a recent article appearing in JAMA Psychiatry, Alex Dombrovski and his colleagues investigated changes in brain signals that may contribute to bad decisions in older suicidal patients...

Phenomenology of Bipolar Disorder Not Otherwise Specified in Youth: A Comparison of Clinical Characteristics across the Spectrum of Manic Symptoms Hafeman D, Axelson D, Demeter C, Findling RL, Fristad MA, Kowatch RA, Youngstrom EA, Horwitz SM, Arnold LE, Frazier TW, Ryan N, Gill MK, Hauser-Harrington JC, Depew J, Rowles BM, Birmaher B Bipolar Disorders, 2013, 15(3):240-252 In the field of child and adolescent...