Publications

Traumatic early-life experiences—emotional, physical, or sexual abuse and/or neglect in childhood—can have an impact on cognitive, emotional, and neurodevelopmental processes years after the events occur, potentially leading to depression and suicidal behavior into adolescence and young adulthood. However, it is unclear whether this same relationship extends into late life. As older adults, especially those 85 and...

Foraging is a type of reward-guided behavior in which a decision is made by weighing potential rewards available in the current environment versus the cost of lost time traveling to a new environment. In other words, when the current setting is less rewarding than the average experience, it is optimal to leave and search for something that is likely to be better. Although striatal dopamine is key to this process...

The Pascoal Lab (PI: Tharick Pascoal, MD, PhD; Associate Professor of Psychiatry and Neurology) and colleagues have published recent research findings in Alzheimer's & Dementia and Nature Aging examining biomarkers and pathophysiological progression of Alzheimer's disease. “These two publications contribute to our understanding of the biomarkers and pathophysiological processes associated with the progression of...

The year following inpatient psychiatric hospitalization—particularly the first three months following discharge—are a period of high risk for suicidal behavior among psychiatric patients. Prior history of suicidal behavior, mood, anxiety, substance use, and post-traumatic stress disorders contribute to risk for future suicidal behavior within this population. Psychosocial stressors also contribute to risk for...

In a recent paper published in the Journal of the American Academy of Child & Adolescent Psychiatry, Christian Porter (PhD student, Pitt School of Social Work); and Tushita Mayanil, MBBS (MD) (Assistant Professor of Psychiatry); Tina Gupta, PhD (postdoctoral scholar); and Leslie Horton, PhD (Assistant Professor of Psychiatry), from Pitt Psychiatry, outlined the increased presence of dissociative identity disorder...

Loss of control over eating (the ingestion of food accompanied by the perception of being unable to control the amount of food consumed) is the core psychological phenomenon associated with binge eating. Loss of control over eating during pregnancy impacts prenatal health and often co-occurs with depressive symptoms. Importantly, both loss of control over eating and depression during pregnancy confer risk for poor...