Publications

Altered Expression of CDC42 Signaling Pathway Components in Cortical Layer 3 Pyramidal Cells in Schizophrenia Datta D, Arion D, Corradi JP and Lewis DA Biological Psychiatry, 2015, Published Online Cognitive dysfunction in schizophrenia is associated with a lower density of dendritic spines on deep layer 3 pyramidal cells in the dorsolateral prefrontal cortex (DLPFC). These alterations appear to reflect...

Loss of Microtubule Associated Protein 2 Immunoreactivity Linked to Dendritic Spine Loss in Schizophrenia Shelton MA, Newman JT, Gu H, Sampson AR, Fish KN, MacDonald ML, Moyer CE, DiBitetto JV, Dorph-Petersen K-A, Penzes P, Lewis DA and Sweet RA Biological Psychiatry, Published online Microtubule-associated protein 2 (MAP2) is a neuronal protein that plays a role in maintaining dendritic structure through its...

Early starting, aggressive, and/or callous-unemotional? Examining the overlap and predictive utility of antisocial behavior subtypesHyde LW, Burt SA, Shaw DS, Donnellan MB and Forbes EE Journal of Abnormal Psychology, Published Online Antisocial behavior in adolescence predicts problematic outcomes in adulthood. However, researchers have noted marked heterogeneity within the broad group of youth engaging in these...

GABA synthesizing enzymes in calbindin and calretinin neurons in monkey prefrontal cortex Rocco B, Sweet RA, Lewis DA and Fish K Cerebral Cortex, Published Online Non-overlapping groups of cortical GABAergic neurons are identifiable by the presence of calbindin (CB), calretinin (CR) or parvalbumin (PV). Previous findings by investigators in Dr. Ken Fish?s laboratory in the Department of Psychiatry at the University...

Daytime spikes in dopaminergic activity drive rapid mood-cycling in mice Sidor MM, Spencer SM, Dzirasa K, Parekh PK, Tye KM, Warden MR, Arey RN, Enwright III JF, Jacobsen JPR, Kumar S, Remillard EM, Caron MG, Deisseroth K and McClung CA Molecular Psychiatry, 2015 Nov;20(11):1406-19 Disruptions in circadian rhythms and dopaminergic activity are involved in the pathophysiology of bipolar disorder, though their...

White matter structure in youth with behavioral and emotional dysregulation disorders: A probabilistic tractographic study Versace A, Acuff H, Bertocci MA, Bebko G, Almeida JRC, Perlman SB, Leemans A, Schirda C, Aslam H, Dwojak A, Bonar L, Travis M, Gill MK, Demeter C, Diwadkar VA, Sunshine JL, Holland SK, Kowatch RA, Birmaher B, Axelson D, Horwitz SM, Frazier TW, Arnold LE, Fristad MA, Youngstrom EA, Findling RL...