Publications

Temporal Cognitive Decline Associated with Exposure to Infectious Agents in a Population-based, Aging Cohort Nimgaonkar VL, Yolken RH, Wang T, Chung-Chou HC, McClain L, McDade E, Snitz BE and Ganguli M Alzheimers Disease & Associated Disorders, Published Online, 2015 Numerous cross-sectional studies have related exposure to neurotropic infectious agents with cognitive dysfunction in older adults, however, the...

Altered Functioning of Reward Circuitry in Youth Offspring of Parents with Bipolar Disorder Manelis A, Ladouceur CD, Graur S, Monk K, Bonar LK, Hickey MB, Dwojak AC, Axelson D, Goldstein B, Goldstein TR, Bebko G, Bertocci MA, Gill MK, Birmaher B and Phillips ML. Psychological Medicine, 46:197-208, 2016 Offspring of parents with bipolar disorder (BDO) are at higher risk of bipolar disorder than offspring of parents...

White Matter Hyperintensity Accumulation during Treatment of Late-Life Depression Khalaf A, Edelman K, Tudorascu D, Andreescu C, Reynolds CF and Aizenstein H Neuropsychopharmacology. 40:3027-3035, 2015 White matter hyperintensities (WMHs) have been shown to be associated with the development of late-life depression and eventual treatment outcomes. In a study led by University of Pittsburgh medical student Alexander...

Augmenting NMDA Receptor Signaling Boosts Experience-Dependent Neuroplasticity in the Adult Human Brain Forsyth JK, Bachman P, Mathalon DH, Roach BJ, and Asarnow RF Proceedings of the National Academy of Sciences, 2015, Published Online Experience-dependent plasticity is a fundamental property of the brain. It is defined as the capacity of the brain to undergo changes following environmental input and use, and is a...

The effects of aging on circadian patterns of gene expression in the human prefrontal cortex Chen C-Y, Logan RW, Ma T, Lewis DA, Tseng G, Sibille E and McClung CA Proceedings of the National Academy of Science, 2015, Published Online Examination of thousands of genes from nearly 150 human brains shows the circadian rhythm of gene activity changes with aging, according to a first-of-its-kind study conducted by...

White Matter Hyperintensity Accumulation during Treatment of Late-Life Depression Khalaf A, Edelman K, Tudorascu D, Andreescu C, Reynolds CF and Aizenstein H Neuropsychopharmacology. 40:3027-3035, 2015 White matter hyperintensities (WMHs) have been shown to be associated with the development of late-life depression and eventual treatment outcomes. In a study led by University of Pittsburgh medical student Alexander...