Faculty

Bernie J Devlin, PhD

Professor of Psychiatry and Clinical and Translational Science

Contact Details

3811 O'Hara St.
Pittsburgh
 
PA
 
15213
Email
Website
Computational Genetics Program

Education & Training

PhD
Pennsylvania State University Botany

Professional Affiliations

Fellow, American Association for the Advancement of Science
Member, American Society of Human Genetics
Member, Genetics Society of America
Member, International Society for Autism Research

Selected Honors & Awards

MERIT Award, National Institute of Mental Health
Fellow, American Association for the Advancement of Science, Statistics, Section U

Research Interests

Genetics; Statistics; Neurobiology
Selected Research Publications & Products
  1. Sanders SJ, Murtha MT, Gupta AR, Murdoch JD, Raubeson MJ, Willsey AJ, Ercan-Sencicek AG, DiLullo NM, Parikshak NN, Stein JL, Walker MF, Ober GT, Teran NA, Song Y, El-Fishawy P, Murtha R, Choi M, Overton JD, Bjornson RD, Carrierio NJ, Meyer KA, Bilguvar K, Mane SM, Sestan N, Lifton RP, Gnel M, Roeder K, Geschwind D, Devlin B, State MW. Disruptive de novo point mutations, revealed by whole-exome sequencing, are strongly associated with Autism Spectrum Disorders. Nature 485:237-241, 2012. PMID: 22495306
  2. Klei L, Sanders SJ, Murtha MT, Hus V, Lowe JK, Willsey AJ, Moreno-De-Luca D, Yu TW, Fombonne E, Geschwind D, Grice DE, Ledbetter DH, Lord C, Mane SM, Lese Martin C, Martin DM, Morrow EM, Walsh CA, Melhem NM, Chaste P, Sutcliffe JS, State MW, Cook EH Jr, Roeder K, Devlin B. Common genetic variants, acting additively, are a major source of risk for autism. Molecular Autism 3:9, 2012.PMID: 23067556
  3. Gaugler T, Klei L, Sanders SJ, Bodea CA, Goldberg AP, Lee AB, Mahajan M, Manaa D, Pawitan Y, Reichert J, Ripke S, Sandin S, Sklar P, Svantesson O, Reichenberg A, Hultman CM, Devlin B, Roeder K, Buxbaum JD. Most genetic risk for autism resides with common variation. Nature Genetics 46:881-885, 2014. PMID: 25038753
  4. De Rubeis S, He X, Goldberg AP, Poultney CS, Samocha K, Ercument Cicek A, Kou Y, Liu L, Fromer M, Walker S, Singh T, Klei L, Kosmicki J, Fu SC, Aleksic B, Biscaldi M, Bolton PF, Brownfeld JM, Cai J, Campbell NG, Carracedo A, Chahrour MH, Chiocchetti AG, Coon H, Crawford EL, Crooks L, Curran SR, Dawson G, Duketis E, Fernandez BA, Gallagher L, Geller E, Guter SJ, Sean Hill R, Ionita-Laza I, Jimenez Gonzalez P, Kilpinen H, Klauck SM, Kolevzon A, Lee I, Lei J, Lehtimki T, Lin CF, Ma'ayan A, Marshall CR, McInnes AL, Neale B, Owen MJ, Ozaki N, Parellada M, Parr JR, Purcell S, Puura K, Rajagopalan D, Rehnstrm K, Reichenberg A, Sabo A, Sachse M, Sanders SJ, Schafer C, Schulte-Rther M, Skuse D, Stevens C, Szatmari P, Tammimies K, Valladares O, Voran A, Wang LS, Weiss LA, Jeremy Willsey A, Yu TW, Yuen RK; The DDD Study; Homozygosity Mapping Collaborative for Autism; UK10K Consortium; The Autism Sequencing Consortium, Cook EH, Freitag CM, Gill M, Hultman CM, Lehner T, Palotie A, Schellenberg GD, Sklar P, State MW, Sutcliffe JS, Walsh CA, Scherer SW, Zwick ME, Barrett JC, Cutler DJ, Roeder K, Devlin B, Daly MJ, Buxbaum JD. Synaptic, transcriptional and chromatin genes disrupted in autism. Nature, 515:209-215, 2014. PMID: 25363760
  5. Bodea CA, Neale BM, Ripke S; International IBD Genetics Consortium, Daly MJ, Devlin B, Roeder K. A Method to Exploit the Structure of Genetic Ancestry Space to Enhance Case-Control Studies. American Journal of Human Genetics, 98:857-868, 2016. PMID: 27087321

Clinical Interests

Autism, genetics, and neurobiology; Schizophrenia, genetics, and neurobiology

Education Interests

Pre- and post-doctoral research

The Department of Psychiatry’s 19th Annual Research Day: A Day to Teach, Learn and Be Inspired

2019 Pitt Psychiatry Research Day

The 19th annual Department of Psychiatry Research Day on June 13, 2019 was our biggest yet! For the 505 faculty, postdoctoral students, residents, graduate students and staff who attended, the morning poster session and afternoon program offered a stimulating day of research and career development that was equal parts enlightenment, inspiration, fun and, at times, surprise. The morning session featured 140 posters...

Publications by Department of Psychiatry Faculty Rank Among the Top 1% of Cited Works in 2018

2018 Highly Cited Psychiatry Researchers

Pictured above (left to right): Drs. William Klunk, David Lewis, Mary Phillips, Boris Birmaher, and Bernie Devlin The Department of Psychiatry is proud to announce that five current members of the faculty have been named Highly Cited Researchers for 2018: Boris Birmaher, MD; Bernie J. Devlin, PhD; William E. Klunk, MD, PhD; David A. Lewis, MD; and Mary L. Phillips, MD. Distinguished Emeritus Professor David J...

Pitt Psychiatry Researchers and Colleagues Publish Findings of the Largest Study to Date for Whole-Genome Sequencing in Autism in the Journal Science

Devlin and Colleagues Science 2018

Department of Psychiatry researchers and their colleagues recently published findings from the largest study to date for whole-genome sequencing in autism in the journal Science. The article is one of the first papers released in the initial round of results to emerge from the National Institute of Mental Health’s PsychENCODE Consortium — a nationwide research effort that seeks to decipher how noncoding DNA, often...