Greg J Siegle, PhD

Professor of Psychiatry, Clinical and Translational Science, and SHRS Communication Science and Disorders

Areas of Expertise

  • Mood Disorders
  • Anxiety, OCD & Trauma Disorders
  • AI & Computational Methods
Greg Siegle, PhD

Expertise & Interests

Research Interests

Neural mechanisms of mood disorders; Neural mechanisms of recovery; Targeted interventions

Clinical Interests

Depression; Autism; PTSD; Dissociation

Education Interests

Research mentorship; Medical student education; Translation from lab to clinic

Selected Publications

  1. Mazefsky CA, Conner CM, Siegle GJ, Scott LN, Bylsma LM, Beck KB, Antezana L, Hu X, Cohen A, Borue X, Handen B (in press). Advancing research on suicide and mental health in autistic adults through a Research Domain Criteria (RDoC)-inspired framework. Autism in Adulthood.
  2. Ganesan S, Barrios FA, Batta I, Bauer CCC, Braver TS, Brewer JA, Brown KW, Cahn R, Cain JA, Calhoun VD, Cao L, Chetelat G, Ching CRK, Creswell JD, Dagnino PD, Davanger S, Davidson RJ, Deco G, Dutcher JM, Escrichs A, Eyler LT, Fani N, Farb NAS, Fialoke S, Fresco DM, Garg R, Garland EL, Goldin P, Hafeman DM, Jahanshad N, Kang Y, Khalsa SS, Kirlic N, Lazar SW, Lutz A, McDermott TJ, Pagnoni G, Piguet C, Prakash RS, Rahrig H, Reggente N, Saccaro LF, Sacchet MD, Siegle GJ, Tang YY, Thomopoulos SI, Thompson PM, Torske A, Treves IN, Tripathi V, Tsuchiyagaito A, Turner MD, Vago DR, Valk S, Zeidan F, Zalesky A, Turner JA, King AP. (2024).ENIGMA-Meditation: Worldwide consortium for neuroscientific investigations of meditation practices, Biological Psychiatry: Cognitive Neuroscience and Neuroimaging,
  3. Brandeis BO, Siegle GJ, Franzen P, Soehner A, Hasler B, McMakin D, Young K, Buysse DJ. (2023) Subjective and neural reactivity during savoring and rumination. Cognitive, Affective, and Behavioral Neuroscience, 23, 1568-1580. https://doi.org/10.3758/s13415-023-01123-2
  4. Compere L, Siegle GJ, Riley E, Lazzaro S, Strege M, Pacoe B, Canovali G, Barb S, Huppert T, Young K. (2023). Enhanced efficacy of CBT following augmentation with amygdala rtfMRI neurofeedback in depression. Journal of Affective Disorders, 339, 495-501. PMID: 37459978; PMCID: PMC10530481. doi: 10.1016/j.jad.2023.07.063.
  5. Fani N, Guelfo A, La Barrie DL, Teer AP, Clendinen C, Karimzadeh L, Jain J, Ely TD, Powers A, Bradley B, Siegle GJ. (2023) Neurophysiological changes associated with vibroacoustically augmented breath-focused mindfulness for dissociation: Targeting interoception and attention. Psychological Medicine, 53(16):7550-7560. PMID: 37339817 PMCID: PMC10281719, doi: 10.1017/S0033291723001277.
  6. Beevers CG, Berwian IM, Blackwell SE, Bockting CL, Brakemeier EL, Brown G, Buckman JEJ, Castonguay LG, Cusack CE, Dalgleish T, de Jong K, Delgadillo J, DeRubeis RJ, Driessen E, Ehrenreich-May J. Fisher AJ, Fried EI, Fritz J, Furukawa TA, Gillan CM, Gmez Penedo JM, Hitchcock PF, Hofmann SG, Hollon SD, Jacobson NC, Karlin DR, Lee CT, Levinson CA, Lorenzo-Luaces L, McDanal R, Moggia D, Ng MY, Norris LA, Patel V, Piccirillo ML, Pilling S, Rubel JA, Salazar-de-Pablo G, Schleider JL, Schnurr PP, Schueller SM, Siegle GJ, Uher R, Watkins E, Webb CA, Wiltsey Stirman S, Wynants L, Youn SJ, Zilcha-Mano S, Lutz W & Cohen ZD. (2024). Implementing precision methods in personalizing psychological therapies: Barriers and possible ways forward. Behaviour Research and Therapy. 172:104443 doi: https://doi.org/10.1016/j.brat.2023.104443.
  7. Li H, Goldin P, Siegle GJ. (2022). Neuroscience for clinicians: Translational clinical neuroscience to inspire clinical practice and research. In Hofmann, S. (Ed). Comprehensive Clinical Psychology, 2nd Ed., 1.08, 145-167, Elsevier, New York, NY., https://doi.org/10.1016/B978-0-12-818697-8.00190-4
  8. Richey JA, Ellard KK, Siegle GJ, Price RB, Mohlman J, de Raedt R, Browning M, Weissman AS. Closing the gap between science and practice: Report from the Neurocognitive Therapies/ Translational Research (NT/TR) Special Interest Group. The Behavior Therapist. 2013;36:158-160.
  9. Fang A, Anderson RE, Carter S, Eckstrand K, Hsu KJ, Jones S, Kyryza-Lacombe M, Pekham A, Siegle GJ, Uddin LQ, Weierich M, Woody M, Illes J. (In press). Bioethical and critical consciousness in clinical translational neuroscience, Journal of Clinical and Translational Science.
  10. Zhang M, Siegle GJ. (2023) Linking affective and hearing sciences Affective audiology. Trends in Hearing, 27. https://doi.org/10.1177/23312165231208377
  11. Siegle GJ & Coan J. (2018). Neuroscience relevant to core processes in psychotherapy. In Hayes, S. & Hofmann, S. Process Based CBT: The Science and Core Clinical Competencies of Cognitive Behavioral Therapy. New Harbinger Publications, Oakland, CA.
  12. Hansen, N. & Siegle, G.J. (2015). Paving the Road to the Neurocognitive Clinic of Tomorrow: Standards and Milestones. In Mohlman, J., Deckersbach, T., & Weissman, A. (Eds). Clinical Psychology: A Neurocognitive Perspective. New York, Routledge.
  13. Siegle, G.J., Johnson, S. L., Everhart, D.E., Newton, T. (2010). Tips on writing National Research Service Award Predoctoral Fellowship proposals from real NRSA reviewers. The Behavior Therapist, 33, 160-164.

Education & Credentials

Education & Training

Education
PhD, Clinical Psychology, San Diego State University/University of California, San Diego
Internship
Psychiatry, Center for Addiction and Mental Health, Toronto, Canada
Postdoctoral
Cognitive Clinical Neuroscience, University of Pittsburgh

Professional Affiliations

  • Member, Society for Affective Science
  • Member, Society of Biological Psychiatry
  • Member, Association for Behavioral and Cognitive Therapies