Faculty

Fabio Ferrarelli, MD, PhD

Fabio Ferrarelli, MD, PhD

Associate Professor of Psychiatry

Contact Details

3811 O'Hara St.
Pittsburgh
 
PA
 
15213
Email
Website
PyNeL

Education & Training

MD
Catholic University of Sacred Heart, School of Medicine
PhD
Neuroscience, Catholic University of Sacred Heart
Psychiatry, Western Psychiatry Institute and Clinic of UPMC
Neuroscience, University of Wisconsin, Madison

Specialty Certifications

Board Certification
American Board of Psychiatry and Neurology

Current Appointments

Director, Sleep and Schizophrenia Program

Selected Honors & Awards

Outstanding Resident Award, National Institute of Mental Health
Rising Star Award, Pittsburgh Foundation

Research Interests

Biomarkers of schizophrenia & psychosis; Sleep oscillations; Neuromodulation (i.e. TMS, TBS)
Selected Research Publications & Products
  1. Mayeli A, LaGoy AD, Smagula SF, Wilson JD, Zarbo C, Rocchetti M, Starace F, Zamparini M, Casiraghi L, Calza S, Rota M, D'Agostino A, de Girolamo G; DiAPAson Consortium; Ferrarelli F. Shared and distinct abnormalities in sleep-wake patterns and their relationship with the negative symptoms of Schizophrenia Spectrum Disorder patients. Mol Psychiatry. 2023 May;28(5):2049-2057. doi: 10.1038/s41380-023-02050-x. Epub 2023 Apr 14. PMID: 37055512
  2. Bagautdinova J, Mayeli A, Wilson JD, Donati FL, Colacot RM, Meyer N, Fusar-Poli P, Ferrarelli F. Sleep abnormalities in different clinical stages of psychosis: A systematic review and Meta-analysis. JAMA Psychiatry. 2023 Mar 1;80(3):202-210. doi: 10.1001/jamapsychiatry.2022.4599. PMID: 36652243
  3. Mayeli A, Wilson JD, Donati FL, LaGoy AD, Ferrarelli F. Sleep spindle alterations relate to working memory deficits in individuals at clinical high-risk for psychosis. Sleep. 2022 Nov 9;45(11):zsac193. doi: 10.1093/sleep/zsac193. PMID: 35981865
  4. Ferrarelli F, Phillips ML. Examining and modulating neural circuits in psychiatric disorders with transcranial magnetic stimulation and electroencephalography: Present practices and future developments. Am J Psychiatry. 2021 May 1;178(5):400-413. doi: 10.1176/appi.ajp.2020.20071050. Epub 2021 Mar 3. PMID: 33653120
  5. Quiones GM, Mayeli A, Yushmanov VE, Hetherington HP, Ferrarelli F. Reduced GABA/glutamate in the thalamus of individuals at clinical high risk for psychosis. Neuropsychopharmacology. 2021 May;46(6):1133-1139. doi: 10.1038/s41386-020-00920-4. Epub 2020 Dec 3.

Clinical Interests

Early course psychosis; Sleep disturbances in psychiatric disorders; Interventional psychiatry
Selected Clinical Publications & Products
  1. Kaskie RE, Ferrarelli F. Investigating the neurobiology of schizophrenia and other major psychiatric disorders with Transcranial Magnetic Stimulation. Schizophr Res. 2017 May 3. PMID: 28478887
  2. Sprecher KE, Ferrarelli F, Benca RM. Sleep and plasticity in schizophrenia. Curr Top Behav Neurosci. 2015; 25: 433-58. PMID: 25608723
  3. Ferrarelli F. Endophenotypes and biological markers of schizophrenia: from biological signs of illness to novel treatment targets. Curr Pharm Des. 2013; 19(36):6462-79. PMID: 23432712
  4. Ferrarelli F & Benca RM (2010): Neurophysiology and neuroimaging of human sleep. In Winkelman & Plante (Eds.), Foundations of Psychiatric Sleep Medicine (chapter 3). Cambridge, UK: Cambridge University Press
  5. Ferrarelli F (2009): The application of TMS in the treatment of obsessive-compulsive and schizophrenia disorders. In J. Mally (Ed.) The Repetitive Transcranial Magnetic Stimulation (rTMS) in the Treatment and Rehabilitation of Central Nervous Diseases, (chapter 19). Budapest, Hu: Eurobridge Co

Education Interests

Research mentorship; Medical student & resident education

Psychiatry Residents Present Robust Research at the 7th Annual Psychiatry Research Pathway Symposium

PRP Residents and Mentors

The Psychiatry Research Pathway (PRP) Symposium provides UPMC Western Psychiatric Hospital residents engaged in research the opportunity to present their work to fellow residents, faculty mentors, T32 postdoctoral research program directors, and interested members of our academic community. This year, the PRP Symposium began with a panel discussion focused on interventional psychiatry, moderated by Katherine Lyman...

Pitt Psychiatry Establishes Center for Neural Circuit-Based Technology Interventions in Psychiatry

Faculty of the New CNCTI-P Center

The Department of Psychiatry has established a Center for Neural Circuit-Based Technology Interventions in Psychiatry (CNCTI-P), which will be led by Mary Phillips, MD, MD (CANTAB) (Distinguished Professor of Psychiatry, Clinical and Translational Science, and Bioengineering, and Pittsburgh Foundation-Emmerling Endowed Chair in Psychotic Disorders). Dr. Phillips is an international leader in affective neuroscience...

Pitt Psychiatry Hosts First Interventional Psychiatry Showcase

Interventional Psychiatry Showcase Classroom Mosaic

Interventional psychiatry is a major focus for many Pitt Psychiatry clinical and research faculty members. In the clinical environment, interventional psychiatry entails the development and implementation of novel psychiatric treatments using devices and innovative pharmacology, alone or with cognitive or behavioral treatment strategies. In interventional psychiatry research, investigators marry technology...

Pitt Psychiatry News from the 2023 American College of Neuropsychopharmacology Annual Meeting

2023 ACNP Annual Meeting Collage

Many University of Pittsburgh Department of Psychiatry faculty and trainees attended the 2023 American College of Neuropsychopharmacology (ACNP) annual meeting to learn about and present new research, and connect with colleagues. Below is a recap of Pitt Psychiatry news from the meeting: Honorific Award Mary Phillips, MD, MD (Cantab) (Distinguished Professor of Psychiatry, Clinical and Translational Science, and...

Molecular Psychiatry: Shared and Distinct Abnormalities in Sleep-Wake Patterns and Their Relationship with the Negative Symptoms of Schizophrenia Spectrum Disorder Patients

Dr, Fabio Ferrarelli

Sleep and rest-activity-rhythm abnormalities are commonly reported in schizophrenia spectrum disorder patients. However, an in-depth characterization of sleep and rest-activity-rhythm alterations in schizophrenia spectrum disorder, including patients in different treatment settings, and the relationship between these alterations and schizophrenia spectrum disorder clinical features, is lacking. Characterization of...