Faculty

Neal D Ryan, MD

Joaquim Puig-Antich Professor in Child and Adolescent Psychiatry and Professor of Clinical and Translational Science

Contact Details

121 Meyran Avenue
Pittsburgh
 
PA
 
15213
Phone 412 383-5478
Email

Education & Training

MD
Yale University, School of Medicine
Psychiatry, New York State Psychiatric Institute, Columbia University
Child Psychiatry, Western Psychiatric Institute and Clinic of UPMC

Specialty Certifications

Board Certification
American Board of Psychiatry and Neurology (Child and Adolescent Psychiatry)

Current Appointments

Director of Education, Department of Psychiatry

Professional Affiliations

Fellow, American Academy of Child and Adolescent Psychiatry
Member, American College of Neuropsychopharmacology
Member, Society of Biological Psychiatry

Research Interests

Machine learning and big data in psychiatry
Selected Research Publications & Products
  1. Posada JD, Barda AJ, Xue D, Ruiz V, Ryan ND, Tsui FR. Predictive modeling for classification of positive valence system symptom severity from initial psychiatric evaluation records. J Biomed Inform. 2017 May 29. doi: 10.1016/j.jbi.2017.05.019.
  2. Silk JS, Tan PZ, Ladouceur CD, Meller S, Siegle GJ, McMakin DL, Forbes EE, Dahl RE, Kendall PC, Mannarino A, Ryan ND. A Randomized Clinical Trial Comparing Individual Cognitive Behavioral Therapy and Child-Centered Therapy for Child Anxiety Disorders. J Clin Child Adolesc Psychol. 2016 Mar 16:1-13. PMID:26983904
  3. Ryan ND, Kim JW, Leventhal BL. What To Do When It Is not so Clear What To Do: New Opportunities for Studies. J Child Adolesc Psychopharmacol. 2012 Dec;22(6):463-5. doi: 10.1089/cap.2012.2262. PMID:23234590
  4. Kim J, Sharma V, Ryan ND. Predicting methylphenidate response in ADHD using machine learning approaches. The international journal of neuropsychopharmacology. 2015. May 10; 18(11) DOI: 10.1093/ijnp/pyv052
  5. Forbes EE, Phillips ML, Silk JS, Ryan ND, Dahl RE. Neural systems of threat processing in adolescents: role of pubertal maturation and relation to measures of negative affect. Dev Neuropsychol. 2011 May;36(4):429-52. PMID: 21516542

Clinical Interests

Childhood/adolescent depression & anxiety

Education Interests

Research mentorship of early career faculty; Research design mentoring; Machine learning and big data in psychiatry
Selected Education Publications & Products
  1. Saunders J, Gopalan P, Puri N, Azzam PN, Zhou L, Ghinassi F, Jain A, Travis M, Ryan ND. Psychosomatic Medicine for Non-Psychiatric Residents: Video Educationand Incorporation of Technology. Acad Psychiatry. 2015 Dec;39(6):649-53. doi:10.1007/s40596-015-0311-3. Epub 2015 Mar 31. PubMed PMID: 25825227.
  2. Jacobson SL, Travis MJ, Solai L, MacPhee E, Reynolds CF 3rd, Ryan ND, Roth LH, Kupfer DJ. Preparing the next generation of leaders in clinician-education andacademic administration. Acad Psychiatry. 2010 May-Jun;34(3):224-8. doi:10.1176/appi.ap.34.3.224. PubMed PMID: 20431105.
  3. Gilbert AR, Tew JD Jr, Reynolds CF 3rd, Pincus HA, Ryan N, Nash K, Kupfer DJ. A developmental model for enhancing research training during psychiatry residency. Acad Psychiatry. 2006 Jan-Feb;30(1):55-62. PubMed PMID: 16473996.
  4. Reynolds CF 3rd, Martin C, Brent D, Ryan N, Dahl RE, Pilkonis P, Marcus MD, Kupfer DJ. Postdoctoral clinical-research training in psychiatry: A model for teaching grant writing and other research survival skills and for increasingclarity of mentoring expectations. Acad Psychiatry. 1998 Sep;22(3):190-6. doi:10.1901/jaba.1998.22-190. PubMed PMID: 19617924; PubMed Central PMCID:PMC2711541.

Science Translational Medicine: Sleep-Sensitive Dopamine Receptor Expression in Male Mice Underlies Attention Deficits After a Critical Period of Early Adversity

Cameron and Colleagues Science: Translational Medicine 2024

In both children and animal models, adverse childhood experiences lead to cognitive and behavioral impairments that have profound influence on behavior and health throughout the lifespan. To improve our understanding of the long-lasting impact of early stress exposure, the specific brain circuits impacted by early stress, and the mechanisms underlying each aspect of the influence of stress exposure, investigators...

The Developmental Affective Neuroscience Symposium: Presenting Translational Research in Developmental Psychopathology

The Developmental Affective Neuroscience Symposium Collage

The Developmental Affective Neuroscience Symposium (DANS) presents recent translational research in developmental psychopathology. The 2023 DANS theme was “ Neurodevelopment of Regulatory Systems: A Focus on Emotions and Motivation,” featuring research focused on the development of neural networks and circuitries implicated in regulating or modulating neural response to emotionally or motivationally salient...

Pitt Psychiatry Awarded $16.2M National Institute of Mental Health Center Grant Focused on Addressing Adolescent Suicide, with Focus on Black and Hispanic Youth

ETUDES Investigators

The National Institute of Mental Health (NIMH) has awarded Pitt Psychiatry a Center of Excellence (P50) grant renewal for Enhancing Triage and Utilization for Depression and Emergent Suicidality (ETUDES), led by David Brent, MD (Distinguished Professor of Psychiatry, Pediatrics, Epidemiology, and Clinical and Translational Science, and Endowed Chair in Suicide Studies). The Center is co-led by Bruce Rollman, MD...

Now in The American Journal of Psychiatry: Neural Reward Circuitry & Psychotherapy in Youths with Anxiety Disorders

Forbes & Colleagues American Journal of Psychiatry 2021

In a recent American Journal of Psychiatry study, Pitt Psychiatry investigators examined the association between function in the brain’s reward circuitry and response to psychotherapy in youths with anxiety disorders. Recent research has indicated the importance of reward in the pathophysiology and treatment of anxiety, suggesting the potential involvement of reward circuitry in treatment response. The team of...

Biological Psychiatry and Journal of Affective Disorders Research in Mood and/or Bipolar Disorders in Adolescence

Biological Psychiatry and Journal of Affective Disorders Research on Adolescent Mental Health

New research from Pitt Psychiatry investigators provides insight into the development of anxiety, depression, and/or bipolar in adolescence. A Biological Psychiatry study examines the association between trauma exposure, reward neural circuitry function, and affective and anxiety disorders. In the Journal of Affective Disorders, investigators study whether child maltreatment and cognitive function influence the...