The Department of Psychiatry Lecture Series features the work of Carrie Bearden, PhD, Professor of Psychology at the University of California, Los Angeles on January 18th. Dr. Bearden will present a Special Guest Lecture highlighting her findings.
Dr. Carrie Bearden's research aims to understand neurobiological risk factors for the development of serious mental illness, using converging methods to study cognition and neuroanatomy in clinical high-risk samples (e.g., adolescents with early symptoms of psychosis), and in highly penetrant genetic subtypes of the illness (e.g., 22q11.2 microdeletions). Her recent work focuses on translational approaches to understanding disrupted brain circuitry in developmental neuropsychiatric disorders, particularly in the context of unique genetic populations. The study of risk factors for psychosis has been approached through multiple avenues, including studies of youth at clinical high risk for the disorder and investigations of copy number variants or structural genetic mutations that confer risk. Each approach can inform and provide insight to the other, potentially resulting in synergistic models for understanding the ways in which heterogeneous genetic etiologies can affect brain development and ultimately behavior, converging in a final common pathway to this debilitating disorder. Dr. Bearden will critically evaluate the extent to which genetic and neurodevelopmental factors that place youth at either clinical or genetic high risk for schizophrenia converge. Findings will be presented from multimodal neuroimaging studies of 22q11.2 deletion syndrome (22q11DS), a contiguous gene deletion disorder that conveys the greatest increase in risk for schizophrenia in the population. She will also address parallel findings from the North American Prodrome Longitudinal Study (NAPLS), which has followed approximately 250 youth at clinical high risk for psychosis for 2 1⁄2 years. She will also discuss the commonalities found across these cohorts to identify factors that can lead to early identification of - and mechanistically informed interventions for - individuals who are at heightened genetic or clinical risk.
Learning Objectives: At the conclusion of this lecture, participants will be able to:
Identify risk factors relevant to the development of psychosis in adolescence and early adulthood.
Discuss current knowledge of the genetic architecture of schizophrenia.
Identify points of convergence between different etiologies of psychosis.
The entirety of this program will be a lecture by the speaker(s). All individuals able to control the content of this educational activity are required to disclose all relevant financial relationships with any proprietary entity producing, marketing, re-selling, or distributing health care goods or services, used on, or consumed by, patients. Registration is not required for this event. This event is free and there will be no refunds. The University of Pittsburgh is an affirmative action, equal opportunity institution
Location. UPMC Western Psychiatric Hospital Auditorium.
For More Information. Please contact Frances Patrick (Telephone: 412-246-6787; Email: firstname.lastname@example.org).