Kenneth N Fish, PhD
Education & Training
- Alterations in a Unique Class of Cortical Chandelier Cell Axon Cartridges in Schizophrenia.Rocco BR, DeDionisio AM, Lewis DA, Fish KN.Biol Psychiatry. 2017 Jul 1;82(1):40-48. doi: 10.1016/j.biopsych.2016.09.018. Epub 2016 Sep 29.PMID: 27884423
- Pathological Basis for Deficient Excitatory Drive to Cortical Parvalbumin Interneurons in Schizophrenia.Chung DW, Fish KN, Lewis DA.Am J Psychiatry. 2016 Nov 1;173(11):1131-1139. Epub 2016 Jul 22.PMID: 27444795
- Markedly Lower Glutamic Acid Decarboxylase 67 Protein Levels in a Subset of Boutons in Schizophrenia.Rocco BR, Lewis DA, Fish KN.Biol Psychiatry. 2016 Jun 15;79(12):1006-15. doi: 10.1016/j.biopsych.2015.07.022. Epub 2015 Aug 7.PMID: 26364548
- GABA-Synthesizing Enzymes in Calbindin and Calretinin Neurons in Monkey Prefrontal Cortex.Rocco BR, Sweet RA, Lewis DA, Fish KN.Cereb Cortex. 2016 May;26(5):2191-2204. doi: 10.1093/cercor/bhv051. Epub 2015 Mar 30.PMID: 25824535
- Parvalbumin-containing chandelier and basket cell boutons have distinctive modes of maturation in monkey prefrontal cortex.Fish KN, Hoftman GD, Sheikh W, Kitchens M, Lewis DA.J Neurosci. 2013 May 8;33(19):8352-8. doi: 10.1523/JNEUROSCI.0306-13.2013.PMID: 23658174
New Research in Biological Psychiatry & Cerebral Cortex
Two recent studies from the Department of Psychiatry have enhanced our understanding of the role of cortical GABA neurons in health and disease. In Biological Psychiatry, Pitt Psychiatry investigators analyzed indices of parvalbumin-expressing basket cells axon terminals across regions of the visuospatial working memory network in schizophrenia. A paper published in Cerebral Cortex examines GABA neuron transcript...
Recent Study in Science Advances Reports Discovery of Ribosome-Associated Vesicles, a Novel Form of Endoplasmic Reticulum
Scientists representing an international consortium of labs—including postdoctoral associate Despoina Aslanoglou, PhD, Kenneth Fish, PhD, and the study’s senior author, Zach Freyberg, MD, PhD, from Pitt Psychiatry—has published a new study in Science Advances, reporting new insights into the organization of the endoplasmic reticulum. The endoplasmic reticulum is a membrane network within a cell that is important in...
Now in The Journal of Neuroscience: Regional Differences among Pyramidal neurons in the Working Memory Cortical Network
Working memory, the ability to maintain a limited amount of information “in mind” to guide everyday thoughts and behaviors, is a core cognitive process. Its function depends on activity in a network of brain areas distributed across the cerebral cortex. Each of these areas display different patterns of activity while information is being maintained. These differences are correlated with, and might depend on...
The Department of Psychiatry’s 19th Annual Research Day: A Day to Teach, Learn and Be Inspired
The 19th annual Department of Psychiatry Research Day on June 13, 2019 was our biggest yet! For the 505 faculty, postdoctoral students, residents, graduate students and staff who attended, the morning poster session and afternoon program offered a stimulating day of research and career development that was equal parts enlightenment, inspiration, fun and, at times, surprise. The morning session featured 140 posters...