Guillermo R Gonzalez-Burgos, PhD
Education & Training
- Distinct Physiological Maturation of Parvalbumin-Positive Neuron Subtypes in Mouse Prefrontal Cortex. Takeaki Miyamae, Kehui Chen, David A. Lewis and Guillermo Gonzalez-Burgos. Journal of Neuroscience 10 May 2017, 37(19) 4883-4902; DOI: https://doi.org/10.1523/JNEUROSCI.3325-16.2017
- Alterations in Cortical Network Oscillations and Parvalbumin Neurons in Schizophrenia. Guillermo Gonzalez-Burgos, Raymond Y Cho, David A Lewis Biological Psychiatry Volume 77, Issue 12, 15 June 2015, Pages 1031-1040. https://doi.org/10.1016/j.biopsych.2015.03.010.
- Functional maturation of GABA synapses during postnatal development of the monkey dorsolateral prefrontal cortex. Guillermo Gonzalez-Burgos, Takeaki Miyamae, Diego E Pafundo, Hiroki Yoshino, Diana C Rotaru, Gil Hoftman, Dibyadeep Datta, Yun Zhang, Mahjub Hammond, Allan R Sampson, Kenneth N Fish, G Bard Ermentrout, David A Lewis. Cerebral Cortex, Volume 25, Issue 11, 1 November 2015, Pages 40764093, https://doi.org/10.1093/cercor/bhu122
- Glutamate Receptor Subtypes Mediating Synaptic Activation of Prefrontal Cortex Neurons: Relevance for Schizophrenia. Diana C. Rotaru, Hiroki Yoshino, David A. Lewis, G. Bard Ermentrout and Guillermo Gonzalez-Burgos. Journal of Neuroscience 5 January 2011, 31(1)142-156; DOI:https://doi.org/10.1523/JNEUROSCI.1970-10.2011.
- GABA Neurons and the Mechanisms of Network Oscillations: Implications for Understanding Cortical Dysfunction in Schizophrenia. Guillermo Gonzalez-Burgos David A. Lewis. Schizophrenia Bulletin, Volume 34, Issue 5, 1 September 2008, Pages 944961, https://doi.org/10.1093/schbul/sbn070
Now in The Journal of Neuroscience: Regional Differences among Pyramidal neurons in the Working Memory Cortical Network
Working memory, the ability to maintain a limited amount of information “in mind” to guide everyday thoughts and behaviors, is a core cognitive process. Its function depends on activity in a network of brain areas distributed across the cerebral cortex. Each of these areas display different patterns of activity while information is being maintained. These differences are correlated with, and might depend on...
Findings by Dr. Guillermo Gonzalez-Burgos and Dr. David Lewis Indicate that NMDAR Activation Enhances Inhibition of PCs by PVBCs
Understanding the mechanisms by which N-methyl-D-aspartate receptors (NMDARs) regulate cortical circuit function is crucial for testing hypotheses that NMDAR hypofunction is involved in the pathophysiology of schizophrenia. Recent studies reveal that presynaptic NMDARs control transmitter release at cortical synapses, suggesting novel mechanisms of NMDAR action in cortical circuits. If presynaptic NMDARs enhance...
Hot Publication - Miyamae et al.
Distinct physiological maturation of parvalbumin-positive neuron subtypes in mouse prefrontal cortex Miyamae T, Chen K, Lewis DA and Gonzalez Burgos GJournal of Neuroscience, 2017, 37:4883-4902.Parvalbumin-positive (PV+) neurons control the timing of pyramidal cell output in cortical neuron networks. In the prefrontal cortex (PFC), PV+ neuron activity is involved in cognitive function, suggesting that PV+ neuron...
Guillermo Gonzalez-Burgos, PhD Promoted to Associate Professor of Psychiatry by the University of Pittsburgh School of Medicine
Congratulations to Guillermo Gonzalez-Burgos, PhD on his promotion to the rank of Associate Professor of Psychiatry by the University of Pittsburgh School of Medicine.A graduate of the University of Buenos Aires in Argentina, Dr. Gonzalez-Burgos received his PhD in Neuroscience in 1995, and began his career at the University of Pittsburgh later that year. As a postdoc in the Department of Neuroscience, he studied...