Education & Training
Selected Honors & Awards
- Parekh, P.K., Becker-Krail, D., Sundaravelu, P., Ishigaki, S., Okado, H., Sobue, G., Huang, Y., and McClung, C.A. (2017) Altered GluA1 function and accumbal synaptic plasticity in the Clockdelta19 model of bipolar mania. Biological Psychiatry, in press
- Chen, C.Y., Logan, R.W., Tianzhou, M., Lewis, D.A., Tseng, G.C., Sibille, E., and McClung, C.A. (2016) The effects of aging on circadian patterns of gene expression in the human prefrontal cortex. Proc Natl Acad Sci, USA, 113:206-11.
- Sidor, M.M., Spencer, S., Dzirasa, K., Parekh, P.K., Tye, K.M., Warden, M.R., Arey, R.N., Enwright III, J.F., Jacobsen, J.P.R., Kumar, S., Remillard, E.M., Caron, M.G., Deisseroth, K., and McClung, C.A. (2015) Daytime spikes in dopaminergic activity underlie rapid mood-cycling. Molecular Psychiatry, 20:1479-80.
- Ozburn, A.R., Falcon, E., Twaddle, A., Nugent, A.L., Gillman, A.G., Spencer, S.M., Arey, R.N., Mukherjee, S., Lyons-Weiler, J., Self, D.W., and McClung, C.A. (2014) Direct regulation of diurnal Drd3 expression and cocaine reward by NPAS2. Biological Psychiatry 77:425-33. *Selected as a priority communication.
- Arey, R., Enwright III, J.F., Spencer, S., Falcon, E., Ozburn, A.R., and McClung, C.A. (2013) An important role for Cholecystokinin, a CLOCK target gene, in the development and treatment of manic-like behaviors. Molecular Psychiatry, 19: 342-350.
Meet the Neurochicks: This Group of Senior Faculty Members Provide Each Other Support, Encouragement and Good Research Ideas
“During the whole of my training, I had only one female mentor,” remembers Mary Phillips, MD MD (Cantab) (Pittsburgh Foundation-Emmerling Endowed Chair in Psychotic Disorders and Professor of Psychiatry and Clinical and Translational Science). “If you never see a woman as a leader, you risk internalizing the belief that women can’t succeed in that role.” Dr. Phillips counts herself among the Neurochicks, an...
The 5th Annual Sleep & Circadian Science Research Day Presents the Latest in Sleep and Circadian Science Research
Sleep researchers including Pitt Psychiatry faculty, trainees and students gathered in late November at the Pitt University Club to explore new research in the field of sleep and circadian science at the Center for Sleep and Circadian Science Research Day. Adriane Soehner, PhD (Assistant Professor of Psychiatry), chair of the organizing committee that included members across psychiatry, nursing, public health...
Now in Nature Communications: Diurnal Rhythms in Gene Expression in the Prefrontal Cortex in Schizophrenia
Researchers including Pitt Psychiatry investigators Marianne Seney, PhD, and Colleen McClung, PhD, have published a study in Nature Communications describing diurnal rhythms in gene expression in the dorsolateral prefrontal cortex in individuals with schizophrenia, compared with unaffected comparison subjects. Examining the postmortem brains of 46 comparison subjects and 46 subjects with schizophrenia...
Now in The Journal of Neuroscience: Circadian Protein NPAS2 Expression in the Nucleus Accumbens and Cocaine Reward
Disruptions of the circadian clock can contribute to or exacerbate vulnerability to substance use disorder in some populations. The laboratory of Dr. Colleen McClung (Professor of Psychiatry and Clinical and Translational Science) investigates the mechanisms by which circadian genes that regulate mood and impulsivity are involved in the risk for substance abuse. In a recent study published in the Journal of...