Faculty

Helmet T Karim, PhD

Helmet T Karim, PhD

Assistant Professor of Psychiatry and Bioengineering

Contact Details

3811 O'Hara St.
Pittsburgh
 
PA
 
15213
Email
Website
Website

Education & Training

PhD
Bioengineering, University of Pittsburgh, School of Engineering
Geriatric Psychiatry, University of Pittsburgh School of Medicine

Professional Affiliations

Member, Society of Biological Psychiatry
Member, American Association of Geriatric Psychiatry

Research Interests

Prediction of treatment response; Risk assessment in Alzheimer's disease; Novel interventions using TMS
Selected Research Publications & Products
  1. Ly M, Gary ZY, Karim HT, Muppidi NR, Mizuno A, Klunk WE, ... & Alzheimer's Disease Neuroimaging Initiative. (2019). Improving brain age prediction models: incorporation of amyloid status in Alzheimer's disease. Neurobiology of Aging.
  2. Karim HT, Wang M, Andreescu C, Tudorascu D, Butters MA, Karp JF, ... & Aizenstein HJ. (2018). Acute trajectories of neural activation predict remission to pharmacotherapy in late-life depression. NeuroImage: Clinical, 19, 831-839.
  3. Karim HT, Andreescu C, Tudorascu D, Smagula SF, Butters MA, Karp JF, ... & Aizenstein HJ. (2017). Intrinsic functional connectivity in late-life depression: trajectories over the course of pharmacotherapy in remitters and non-remitters. Molecular psychiatry, 22(3), 450-457.
  4. Karim HT, Tudorascu DL, Butters MA, Walker S, Aizenstein HJ, & Andreescu C. (2017). In the grip of worry: Cerebral blood flow changes during worry induction and reappraisal in late-life generalized anxiety disorder. Translational psychiatry, 7(8), e1204-e1204.
  5. Kay DB, Karim HT, Soehner AM, Hasler BP, Wilckens KA, James JA, ... & Germain A. (2016). Sleep-wake differences in relative regional cerebral metabolic rate for glucose among patients with insomnia compared with good sleepers. Sleep, 39(10), 1779-1794.

Clinical Interests

Novel clinical interventions; Maximizing clinical efficacy

Education Interests

Research mentorship; Graduate student advising; Postdoctoral mentorship

Psychiatry Residents Present Robust Research at the 7th Annual Psychiatry Research Pathway Symposium

PRP Residents and Mentors

The Psychiatry Research Pathway (PRP) Symposium provides UPMC Western Psychiatric Hospital residents engaged in research the opportunity to present their work to fellow residents, faculty mentors, T32 postdoctoral research program directors, and interested members of our academic community. This year, the PRP Symposium began with a panel discussion focused on interventional psychiatry, moderated by Katherine Lyman...

Helmet Karim, PhD, Honored by the Organization for Human Brain Mapping

Helmet Karim, PhD, Honored by the Organization for Human Brain Mapping

Congratulations to Helmet Karim, PhD (Assistant Professor of Psychiatry and Bioengineering), who has received the Organization for Human Brain Mapping (OHBM) 2024 Replication Award, which recognizes a replication study relevant to the field of neuroimaging, evaluated based on the quality of the replication attempt and importance of the finding. Dr. Karim was presented with the Award at the OHBM Annual Meeting in...

Pitt Psychiatry’s 2024 Research Day, Part I: A Research and Networking Bonanza

Research Day 2024

The 22nd annual Department of Psychiatry Research Day, held on June 13, 2024, was the most highly attended Research Day ever, with 544 faculty members, trainees, and staff gathering at Soldiers & Sailors Memorial Hall & Museum on the University of Pittsburgh campus. Lunchtime Roundtables More than 260 individuals participated in or facilitated one of 19 roundtable discussion groups focused on topics including...

Pitt Psychiatry Hosts First Interventional Psychiatry Showcase

Interventional Psychiatry Showcase Classroom Mosaic

Interventional psychiatry is a major focus for many Pitt Psychiatry clinical and research faculty members. In the clinical environment, interventional psychiatry entails the development and implementation of novel psychiatric treatments using devices and innovative pharmacology, alone or with cognitive or behavioral treatment strategies. In interventional psychiatry research, investigators marry technology...

The American Journal of Geriatric Psychiatry: White Noise—Is Anxiety in Late-Life Associated With White Matter Hyperintensity Burden?

Drs. Andrew Gerlach and Carmen Andreescu

Anxiety disorders are prevalent in late life, with symptoms including severe (uncontrollable) worry and rumination. Late-life anxiety, worry, and rumination in the context of the aging brain can be associated with differences in volume and thickness of gray matter regions in the brain, as well as altered functional connectivity in the networks involved in emotion generation and regulation, but these changes may...