We regret that the Distinguished Scientist Lecture by Steve McCarroll, PhD, has been cancelled due to a unexpected scheduling conflict.
Dr. McCarroll and the scientists in his lab work to identify the mechanisms by which genetic variation shapes human biology. They seek to develop new ways to make sense of human genetic data and understand how genetic effects manifest in cells and tissues His lab has uncovered surprising ways in which genes and alelles shape risk of human diseases – from schizophrenia (Sekar et al., Nature 2016) to cardiovascular illness (Boettger et al., Nature Genetics 2016) to cancer (Genovese et al., NEJM 2017). Steve’s lab also developed Drop-seq, a widely adopted technology for studying RNA expression in complex tissues (such as the brain) at single-cell resolution
The entirety of this program will be a lecture by the speaker(s). All individuals able to control the content of this educational activity are required to disclose all relevant financial relationships with any proprietary entity producing, marketing, re-selling, or distributing health care goods or services, used on, or consumed by, patients. Registration is not required for this event. This event is free and there will be no refunds. The University of Pittsburgh is an affirmative action, equal opportunity institution.
Location: Western Psychiatric Institute and Clinic Auditorium
For More Information. Please contact Frances Patrick at patrickfm@upmc.edu or at 412-246-6787.
Learning Objectives. At the conclusion of this lecture participants will be able to:
Understand the ebullient genetic variation that affects the complement component 4 genes in the human genome.
Describe how this genetic variation relates to risk of schizophrenia, and what this suggests about potential mechanisms
Understand how this genetic variation relates to risk of autoimmune disease, and what this suggests about potential mechanisms