Faculty

Henry W Chase, PhD

Research Assistant Professor of Psychiatry

Contact Details

3811 O'Hara St.
Pittsburgh
 
PA
 
15213
Email

Education & Training

PhD
Experimental Psychology, University of Cambridge
Psychiatry, University of Pittsburgh School of Medicine
Experimental Psychology, University of Nottingham

Professional Affiliations

Member, Society of Biological Psychiatry

Research Interests

Computational analysis of behavioral performance; Task-based & resting state neuroimaging analysis; Multivariate analysis techniques
Selected Research Publications & Products
  1. Chase HW, Grace AA, Fox PT, Phillips ML, Eickhoff SB. Functional differentiation in the human ventromedial frontal lobe: A data-driven parcellation. Hum Brain Mapp. 2020 Aug 15;41(12):3266-3283. doi: 10.1002/hbm.25014. Epub 2020 Apr 21. PMID: 32314470
  2. Chase HW, Fournier JC, Bertocci MA, Greenberg T, Aslam H, Stiffler R, Lockovich J, Graur S, Bebko G, Forbes EE, Phillips ML. A pathway linking reward circuitry, impulsive sensation-seeking and risky decision-making in young adults: identifying neural markers for new interventions. Translational Psychiatry (2017) 7(4):e1096.
  3. Chase HW, Phillips ML. Elucidating neural network functional connectivity abnormalities in bipolar disorder: Toward a harmonized methodological approach. Biological Psychiatry Cognitive Neuroscience and Neuroimaging (2016) 1(3):288-298.
  4. Chase HW, Nusslock R, Almeida JR, Forbes EE, LaBarbara EJ, Phillips ML. Dissociable patterns of abnormal frontal cortical activation during anticipation of an uncertain reward or loss in bipolar versus major depression. Bipolar Disorders (2013) 15(8):839-854.
  5. Chase HW, Eickhoff SB, Laird AR, Hogarth L. The neural basis of drug stimulus processing and craving: an activation likelihood estimation meta-analysis. Biological Psychiatry (2011) 70(8):785-93.

Clinical Interests

Mood disorders; Neurophysiologcial interventions; Neurophysiological biomarker discovery

Education Interests

Graduate & undergraduate research mentorship

Pitt Psychiatry Establishes Center for Neural Circuit-Based Technology Interventions in Psychiatry

Faculty of the New CNCTI-P Center

The Department of Psychiatry has established a Center for Neural Circuit-Based Technology Interventions in Psychiatry (CNCTI-P), which will be led by Mary Phillips, MD, MD (CANTAB) (Distinguished Professor of Psychiatry, Clinical and Translational Science, and Bioengineering, and Pittsburgh Foundation-Emmerling Endowed Chair in Psychotic Disorders). Dr. Phillips is an international leader in affective neuroscience...

Psychiatry Research: Neural Markers of Mania That Distinguish Inpatient Adolescents with Bipolar Disorder from Those with Other Psychopathology

Drs. Rasim Diler and Michele Bertocci

Adolescents with manic or hypomanic episodes—key features of bipolar disorder (BD)—may experience delayed correct diagnosis or inappropriate treatment because some symptoms of BD are also seen in other disorders (such as unipolar depressive disorders and attention deficit/hyperactive disorder). A team of scientists from the University of Pittsburgh including Michele Bertocci, PhD (Assistant Professor of Psychiatry)...

JAMA Psychiatry: Patterns of Neural Network Functional Connectivity Associated With Mania/Hypomania and Depression Risk in 3 Independent Young Adult Samples 

Drs. Maya Schumer and Mary Phillips

Bipolar disorder, which has peak onset in early adulthood, is often difficult to accurately diagnose due to misreporting mania/hypomania, even though mania/hypomania is a pathognomonic feature of the disorder. The misreporting of this feature frequently results in mistaking bipolar disorder for unipolar depression. To facilitate earlier and accurate bipolar disorder diagnoses, there is a vital need for objective...

Molecular Psychiatry - Prefrontal, Parietal, and Limbic Condition-Dependent Differences in Bipolar Disorder: A Large-Scale Meta-Analysis of Functional Neuroimaging Studies

Maya Schumer and Dr. Mary Phillips

Over the past few decades, neuroimaging research in bipolar disorder has identified neural differences underlying cognitive and emotional processing. However, substantial clinical and methodological heterogeneity across neuroimaging experiments (resulting from differences in healthcare systems, diagnostic subtypes, mood state, treatment response, comorbidity, chronicity, and severity)—as well as additional factors...

Biological Psychiatry and Journal of Affective Disorders Research in Mood and/or Bipolar Disorders in Adolescence

Biological Psychiatry and Journal of Affective Disorders Research on Adolescent Mental Health

New research from Pitt Psychiatry investigators provides insight into the development of anxiety, depression, and/or bipolar in adolescence. A Biological Psychiatry study examines the association between trauma exposure, reward neural circuitry function, and affective and anxiety disorders. In the Journal of Affective Disorders, investigators study whether child maltreatment and cognitive function influence the...