Publications

Corticostriatothalamic Reward Prediction Error Signals and Executive Control in Late-Life Depression Dombrovski AY, Szanto K, Clark L, Aizenstein HJ, Chase HW, Reynolds CF and Siegle GJ Psychological Medicine, 2015, 45(7):1413-24 The vascular depression hypothesis posits that prefrontal disconnection by vascular lesions causes depression and executive dysfunction. In a study recently published in Psychological...

Decreased Delta Sleep Ratio and Elevated Alpha Power Predict Vulnerability to Depression during Interferon-Alpha Treatment Lotrich FE and Germain A Acta Neuropsychiatrica, Volume 40, Supplement, September 2014, Page e2 Although poor sleep sometimes accompanies depression, it is unknown which specific sleep abnormalities precede depression. Drs. Francis Lotrich and Anne Germain prospectively determined which...

Distinctive Transcriptome Alterations of Prefrontal Pyramidal Neurons in Schizophrenia and Schizoaffective Disorder Arion D, Corradi JP, Tang S, Datta D, Boothe F, He A, Cacace AM, Zaczek R, Albright CF, Tseng G and Lewis DA Molecular Psychiatry, Published Online Individuals with schizophrenia experience cognitive problems, such as impaired working memory, in addition to the hallmark symptoms of psychosis. Working...

Prenatal Marijuana Exposure Predicts Marijuana Use in Young Adulthood Sonon KE, Richardson GA, Cornelius JR, Kim KH and Day NL Neurotoxicology Teratology 47:10-15, 2015 Among US males and females 18 to 25 years of age, 52% have used marijuana, 32% have used marijuana within the past year, and 19% have used marijuana in the past month. Marijuana use peaks in the early 20s, and this time period coincides with the...

An Integrated Risk Reduction Intervention Can Reduce Body Mass Index in Individuals Being Treated for Bipolar I Disorder:Results from a Randomized Trial Frank E, Wallace ML, Hall M, Hasler B, Levenson JC, Janney CA, Soreca I, Fleming MC, Buttenfield J, Ritchey FC and Kupfer DJ Bipolar Disorders, Published online December 12, 2014 Bipolar disorder is a chronic disease that is associated with a potentially...

Familial Pathways to Early-Onset Suicide Attempt: A 5.6-Year Prospective Study Brent DA, Melhem NM, Oquendo M, Burke A, Birmaher B, Stanley B, Biernesser C, Keilp J, Kolko D, Ellis S, Porta G, Zelazny J, Iyengar S and Mann JJ. JAMA Psychiatry. Published online December 30, 2014 Suicide is a leading cause of adolescent mortality. Although suicide attempts are strong predictors of suicide and are highly familial, the...