Education & Training
Selected Honors & Awards
- MacDonald ML, Alhassa J, Newman JT, Richard M, Gu H, Kelly RM, Sampson AR, Fish KN, Penzes P, Wills ZP, Lewis DA, Sweet RA. Selective Loss of Smaller Spines in Schizophrenia. American Journal of Psychiatry, In Press.
- MacDonald ML, Ding Y, Newman J, Hemby S, Penzes P, Lewis DA, Yates NA, Sweet RA. Altered glutamate protein co-expression network topology linked to spine loss in the auditory cortex of schizophrenia. Biol Psychiatry. 2015;77:959-968.
- MacDonald ML, Ciccimaro E, Prakash A, Banerjee A, Seeholzer SH, Blair IA, Hahn CG. Biochemical Fractionation and Stable Isotope Dilution Liquid Chromatography-mass Spectrometry for Targeted and Microdomain-specific Protein Quantification in Human Postmortem Brain Tissue. Mol Cell Proteomics. 2012 Dec;11(12):1670-81.
- MacDonald ML, Eaton M, Dudman T, Konradi K. Antipsychotic drugs elevate mRNA levels of presynaptic proteins in the frontal cortex of the rat. Biological Psychiatry. 1;57(9):1041-51, 2005.
Hot Publication - MacDonald et al.
Selective Loss of Smaller Spines in Schizophrenia MacDonald ML, Alhassan J, Newman JT, Richard M, Gu H, Kelly RM, Sampson AR, Fish KN, Penzes P, Wills ZP, Lewis DA and Sweet RA American Journal of Psychiatry, Published online 2017 Deceased density of dendritic spines in adult schizophrenia subjects has been hypothesized to result from increased pruning of excess synapses in adolescence. In vivo imaging studies have...
ACNP Selects Drs. Matthew MacDonald and Fabio Ferrarelli for Travel Awards
Congratulations to Matthew MacDonald, PhD , Assistant Professor of Psychiatry, and Fabio Ferrarelli, MD, PhD , a PGY4 resident in the Psychiatry Research Pathway track, on their receipt of Travel Awards from the American College of Neuropsychopharmacology (ACNP). The researchers were selected for the awards from a pool of 338 submissions received by the organization. The awards will support their participation at...
Matthew MacDonald, PhD Appointed Assistant Professor of Psychiatry Please join is in welcoming Matthew MacDonald, PhD to the University of Pittsburgh Department of Psychiatry faculty. After earning a Bachelor?s degree in Biology from Ogelthorpe University in Atlanta, GA, Dr. MacDonald studied the pathology of bipolar disorder and schizophrenia through mRNA expression in the human brain and peripheral tissue as well...
Hot Publication - Sweet & Colleagues
Loss of Microtubule Associated Protein 2 Immunoreactivity Linked to Dendritic Spine Loss in Schizophrenia Shelton MA, Newman JT, Gu H, Sampson AR, Fish KN, MacDonald ML, Moyer CE, DiBitetto JV, Dorph-Petersen K-A, Penzes P, Lewis DA and Sweet RA Biological Psychiatry, Published online Microtubule-associated protein 2 (MAP2) is a neuronal protein that plays a role in maintaining dendritic structure through its...