Participate in Research

People like you make the difference!

By participating in a research project, you play a part in helping physicians and researchers develop better ways to diagnose and treat people with mental illness. As a research participant, you learn about the causes of specific mental health problems and what can be done to manage these conditions. 

Find a study to participate in: Enter a keyword below (for example, "depression")

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Project Title:
The BRITE Study (Brain Response and Infant & Toddler Emotions)
Principal Investigator:
Judith Morgan, PhD
For Information Contact:
Allison Hoffman and Britt Holdaway, Email: carelab@pitt.edu; Telephone: 412-624-7991 and 412-383-1047
What We Are Studying:
We are examining how maternal depression and parenting impacts child brain development across the first 5 years of life.
Who Is Eligible to Participate:
Biological mothers with or without current depression and their 1 to 3 year old children. We are also recruiting healthy volunteers.
Who Is Not Eligible to Participate:
Mothers with a history of Bipolar Disorder or Psychosis. Children with a developmental delay or disability, such as Autism.
What Participation Involves:
Participants will complete 6-7 laboratory visits over 3 years. During the 1st visit each year, the mother will complete interviews and questionnaires. During the 2nd visit each year, the mother and child will wear a head cap to measure brain response while playing together. If the child is 5 years old in third year, the child will also undergo fMRI scanning.
Do Participants Receive Compensation as Part of the Study:
Yes
What Compensation Do Participants Receive:
Compensation is provided. Please contact Allison Hoffman or Britt Holdaway for more details.
Brochure Location:
Project Title:
Treating insulin resistance as a strategy to improve outcome in refractory bipolar disorder: a randomized, double-blind, placebo-control study of the efficacy of metformin in patients with insulin resistance and non-remitting bipolar illness (TRIO-BD-100)
Principal Investigator:
K.N. Roy Chengappa, M.D.
For Information Contact:
Joan Spinogatti, Telephone: 412-246-5006; Email: spinogattij@upmc.edu
What We Are Studying:
This study is examining whether addition of metformin, a drug used to treat diabetes, may also help improve the symptoms of bipolar illness.
Who Is Eligible to Participate:
Men or Women aged 18 to 90 years old with a diagnosis of bipolar disorder who have insulin resistance.
Who Is Not Eligible to Participate:
Persons diagnosed with diabetes. Additional exclusion criteria can be discussed with research coordinator.
What Participation Involves:
There are 8 visits in this study. At each visit, an evaluation of mood symptoms; weight and blood pressure waist and hip measurements are carried out. At 7 of 8 visits, blood samples are taken to measure fasting blood sugar and insulin levels and a marker to test for inflammation. Measurement of thyroid functions, cholesterol, liver enzymes, blood cell count, and mood stabilizer levels are also carried out at 3 of these visits.
Do Participants Receive Compensation as Part of the Study:
Yes
What Compensation Do Participants Receive:
Participants will earn up $520 for completing the entire study.
Brochure Location:
Project Title:
MISO: Modulation of Ideation of Suicide and Oscillation
Principal Investigator:
Henry Chase, PhD
For Information Contact:
Simona Graur; Email: graurs@upmc.edu; Telephone: 412-256-8693
What We Are Studying:
We are investigating the effects of weak electrical stimulation on brain activity as measured by EEG and behavioral methods.
Who Is Eligible to Participate:
Persons between the ages of 18 and 45 that have experienced suicidal thoughts or have had a suicide attempt (Suicide Group). Persons between the ages of 18 and 45 that have no history of psychiatric disorders (Control Group).
Who Is Not Eligible to Participate:
Individuals are not eligible if they are not between 18-45 years old, have a systemic medical disease, have a history in the last 3 months of illicit substance abuse/dependence, are left/mixed handed, pregnant, prone to panicking in enclosed spaces, have metallic objects in their bodies, have psychotic symptoms, have history of head injury, currently suicidal.
What Participation Involves:
Participants will have a lifetime psychiatric evaluation. Participants will also complete various tasks during which we will also be investigating the effects of weak electrical stimulation on brain activity. The stimulation is applied on the scalp with a non-FDA approved method called tDCS (transcranial Direct Current Stimulation). While almost unnoticeable to you, these currents can still temporarily affect brain activity without causing any known adverse effects. Electrical brain activity will also be measured using EEG, before and after stimulation.
Do Participants Receive Compensation as Part of the Study:
Yes
What Compensation Do Participants Receive:
Participants will have a lifetime psychiatric evaluation. Participants will also complete various tasks during which we will also be investigating the effects of weak electrical stimulation on brain activity. The stimulation is applied on the scalp with a non-FDA approved method called tDCS (transcranial Direct Current Stimulation). While almost unnoticeable to you, these currents can still temporarily affect brain activity without causing any known adverse effects. Electrical brain activity will also be measured using EEG, before and after stimulation.
Brochure Location:
Project Title:
Impact of Cancer on Risk and Resilience (iCARE)
Principal Investigator:
Nadine Melhem, Ph.D.
For Information Contact:
Katie Krancevich, MPH; krancevichk@upmc.edu; 412-683-7258
What We Are Studying:
The purpose of this research is to learn more about the biological and psychological responses to stress in children experiencing parental cancer.
Who Is Eligible to Participate:
Individuals with and without a parent diagnosed with cancer that have children ages 12-17
Who Is Not Eligible to Participate:
Children diagnosed with Addison's disease or Cushing's syndrome
What Participation Involves:
Participants will be asked to complete an interview and questionnaires about mood, feelings, health, suicidal and other behaviors, childhood abuse history, psychiatric problems, and other risk and protective factors. They will also provide body and vital measurements; blood, hair, and salivary samples. Procedures will be completed at an initial visit and repeated two times over 18 months.
Do Participants Receive Compensation as Part of the Study:
Yes
What Compensation Do Participants Receive:
Please contact the study coordinator for more details.
Brochure Location:
Project Title:
A New Statistical Paradigm for Measuring Psychopathology Dimensions in Youth (YCAT Study)
Principal Investigator:
David Brent, MD
For Information Contact:
Brandie George-Milford (Telephone: 412-246-5629 or 412-586-9405; Email: ycat@upmc.edu)
What We Are Studying:
The purpose of the study is to learn more about the assessment of mood and behavior problems in children.
Who Is Eligible to Participate:
Boys and girls 7-17 years old that are in treatment for mood or behavioral problem and their legal guardians/parents.
Who Is Not Eligible to Participate:
Youth with a diagnosis of psychosis or autism are not eligible.
What Participation Involves:
Participation involves one visit, lasting approximately 2 hours, for a youth-parent pair. The visit includes taking the YCAT survey on an iPad and answering between 150-200 questions about health, mood, and behaviors.
Do Participants Receive Compensation as Part of the Study:
Yes
What Compensation Do Participants Receive:
Yes, compensation is provided. Please contact the study coordinator for more details.
Brochure Location:
Project Title:
Family Pathways Research Study
Principal Investigator:
David Brent, MD
For Information Contact:
Nick Curcio, 100 N Bellefield Avenue, BFT 3rd Floor, Pittsburgh, PA 15213 (Telephone: 412-246-5628 or curcion@upmc.edu)
What We Are Studying:
The FAMPATH study aims to learn more about biological markers in males and females, ages 25-60, who have a family history with a history of depression and suicide attempts.
Who Is Eligible to Participate:
Adults age 25-60 who have a parent, sibling, uncle, aunt, or grandparent with a history of depression and suicide attempts and the adult is not taking psychiatric medication.
Who Is Not Eligible to Participate:
Adults with metal implants, dental braces, a pacemaker, or metal prostheses, and adults taking psychiatric medications.
What Participation Involves:
Participants will be asked to complete two office visits and two scan visits. Procedures will include interviews about mental health, neuro-cognitive and stress testing and MRI and PET scans of your brain. 3 follow up phone calls over 12 months.
Do Participants Receive Compensation as Part of the Study:
Yes
What Compensation Do Participants Receive:
Up to $525 for completing all research activities.
Brochure Location: