Participate in Research

People like you make the difference!

By participating in a research project, you play a part in helping physicians and researchers develop better ways to diagnose and treat people with mental illness. As a research participant, you learn about the causes of specific mental health problems and what can be done to manage these conditions. 

Find a study to participate in: Enter a keyword below (for example, "depression")

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Select keyword(s) from the list below:

Project Title:
Depression Treatment Study
Principal Investigator:
Rebecca Price, PhD
For Information Contact:
Michelle Degutis, canlab@pitt.edu, 412-648-6554
What We Are Studying:
Testing an intravenous infusion of ketamine as a novel, multi-component treatment for depression
Who Is Eligible to Participate:
Adults ages 18-60 who are feeling down, low, or depressed and have tried at least one standard antidepressant medication during the current period of depression, without complete success.
Who Is Not Eligible to Participate:
Adults diagnosed with bipolar disease; those unable to safely complete an MRI assessment
What Participation Involves:
Participants will receive an intravenous infusion of ketamine and complete sessions of a computer-based intervention designed to "retrain the brain," or receive placebo treatments; complete clinical interviews, questionnaires, fMRI brains scans and computer-based tasks."
Do Participants Receive Compensation as Part of the Study:
Yes
What Compensation Do Participants Receive:
Participants will be compensated up to $450 for completing the study.
Brochure Location:
Project Title:
Sleep, Circadian Rhythms and Cardiometabolic Risk in Retired Shift Worker
Principal Investigator:
Daniel Buysse, MD
For Information Contact:
Michael Lightfoot, lightfootm@upmc.edu, WPIC E-1136, 3811 O'Hara Street, 15213, 412-246-6419; or Sarah Kimutis, kimutiss@upmc.edu, 412-246-6643.
What We Are Studying:
This study examines the effects of night shift work exposure on heart health, sleep and emotional expression into retirement.
Who Is Eligible to Participate:
Individuals aged >60 years old who have been retired at least 1 year and are medically stable, and have a history of night shift work or a history of daylight work (with little or no night shift work).
Who Is Not Eligible to Participate:
Individuals who are medically or emotionally unstable, or who are insulin dependent diabetics, in current treatment for sleep apnea, using of beta blockers, or using tobacco.
What Participation Involves:
Participants will complete an initial evaluation, medical history and exam, cardiovascular assessment, blood samples, computer assessments. Some participants will completed a 2 1/2 day (60 hour) sleep lab study
Do Participants Receive Compensation as Part of the Study:
Yes
What Compensation Do Participants Receive:
Participants will be compensated up to $450. Please contact the project coordinators for details.
Brochure Location:
Project Title:
The SHINE Study (Shyness & Inhibition in New Experiences)
Principal Investigator:
Judith Morgan, PhD
For Information Contact:
Allison Hoffman and Britt Holdaway, Email: carelab@pitt.edu; Telephone: 412-624-7991 and 412-383-1047
What We Are Studying:
We are studying how preschool age children react to new social experiences and how that is related to shyness.
Who Is Eligible to Participate:
Biological parents and their 3 to 5 year old children. We are also recruiting healthy volunteers.
Who Is Not Eligible to Participate:
Children with developmental delay or disability, such as Autism.
What Participation Involves:
Participants will complete 2 laboratory visits. Visit 1: Parent completing interviews and questionnaires. Visit 2: Parent and child will wear a head cap that measures brain response while playing together; 6 and 12 months later, the parent will complete online questionnaires. Optional: Inviting one additional caregiver to complete online questionnaires about child at baseline, 6 months, and 12 months.
Do Participants Receive Compensation as Part of the Study:
Yes
What Compensation Do Participants Receive:
Compensation is provided. Please contact Allison Hoffman or Britt Holdaway for more details.
Brochure Location:
Project Title:
The BRITE Study (Brain Response and Infant & Toddler Emotions)
Principal Investigator:
Judith Morgan, PhD
For Information Contact:
Allison Hoffman and Britt Holdaway, Email: carelab@pitt.edu; Telephone: 412-624-7991 and 412-383-1047
What We Are Studying:
We are examining how maternal depression and parenting impacts child brain development across the first 5 years of life.
Who Is Eligible to Participate:
Biological mothers with or without current depression and their 1 to 3 year old children. We are also recruiting healthy volunteers.
Who Is Not Eligible to Participate:
Mothers with a history of Bipolar Disorder or Psychosis. Children with a developmental delay or disability, such as Autism.
What Participation Involves:
Participants will complete 6-7 laboratory visits over 3 years. During the 1st visit each year, the mother will complete interviews and questionnaires. During the 2nd visit each year, the mother and child will wear a head cap to measure brain response while playing together. If the child is 5 years old in third year, the child will also undergo fMRI scanning.
Do Participants Receive Compensation as Part of the Study:
Yes
What Compensation Do Participants Receive:
Compensation is provided. Please contact Allison Hoffman or Britt Holdaway for more details.
Brochure Location:
Project Title:
MISO: Modulation of Ideation of Suicide and Oscillation
Principal Investigator:
Henry Chase, PhD
For Information Contact:
Simona Graur; Email: graurs@upmc.edu; Telephone: 412-256-8693
What We Are Studying:
We are investigating the effects of weak electrical stimulation on brain activity as measured by EEG and behavioral methods.
Who Is Eligible to Participate:
Persons between the ages of 18 and 45 that have experienced suicidal thoughts or have had a suicide attempt (Suicide Group). Persons between the ages of 18 and 45 that have no history of psychiatric disorders (Control Group).
Who Is Not Eligible to Participate:
Individuals are not eligible if they are not between 18-45 years old, have a systemic medical disease, have a history in the last 3 months of illicit substance abuse/dependence, are left/mixed handed, pregnant, prone to panicking in enclosed spaces, have metallic objects in their bodies, have psychotic symptoms, have history of head injury, currently suicidal.
What Participation Involves:
Participants will have a lifetime psychiatric evaluation. Participants will also complete various tasks during which we will also be investigating the effects of weak electrical stimulation on brain activity. The stimulation is applied on the scalp with a non-FDA approved method called tDCS (transcranial Direct Current Stimulation). While almost unnoticeable to you, these currents can still temporarily affect brain activity without causing any known adverse effects. Electrical brain activity will also be measured using EEG, before and after stimulation.
Do Participants Receive Compensation as Part of the Study:
Yes
What Compensation Do Participants Receive:
Participants will have a lifetime psychiatric evaluation. Participants will also complete various tasks during which we will also be investigating the effects of weak electrical stimulation on brain activity. The stimulation is applied on the scalp with a non-FDA approved method called tDCS (transcranial Direct Current Stimulation). While almost unnoticeable to you, these currents can still temporarily affect brain activity without causing any known adverse effects. Electrical brain activity will also be measured using EEG, before and after stimulation.
Brochure Location:
Project Title:
Impact of Cancer on Risk and Resilience (iCARE)
Principal Investigator:
Nadine Melhem, Ph.D.
For Information Contact:
Katie Krancevich, MPH; krancevichk@upmc.edu; 412-683-7258
What We Are Studying:
The purpose of this research is to learn more about the biological and psychological responses to stress in children experiencing parental cancer.
Who Is Eligible to Participate:
Individuals with and without a parent diagnosed with cancer that have children ages 12-17
Who Is Not Eligible to Participate:
Children diagnosed with Addison's disease or Cushing's syndrome
What Participation Involves:
Participants will be asked to complete an interview and questionnaires about mood, feelings, health, suicidal and other behaviors, childhood abuse history, psychiatric problems, and other risk and protective factors. They will also provide body and vital measurements; blood, hair, and salivary samples. Procedures will be completed at an initial visit and repeated two times over 18 months.
Do Participants Receive Compensation as Part of the Study:
Yes
What Compensation Do Participants Receive:
Please contact the study coordinator for more details.
Brochure Location: