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Project Title:
Anhedonia Development in LGB Youth
Principal Investigator:
Erika Forbes, Ph.D.
For Information Contact:

Marissa Cross: crossma@upmc.edu; 412-589-9013

What We Are Studying:
We are assessing various levels of anhedonia (the loss of interest or pleasure in daily life and activities) in LGB teens and how it affects brain function.
Who Is Eligible to Participate:
Adolescents ages 16-20 who experience same-sex attraction and who have a parent willing to participate. To see if you are eligible, follow this link: https://pitt.co1.qualtrics.com/SE/?SID=SV_0JxOhPoUjwwV0XP
Who Is Not Eligible to Participate:
Adolescents must not smoke every day or have a history of head trauma.
What Participation Involves:
Parents will complete questionnaires. Adolescents will complete interviews, questionnaires, computer tasks, and an fMRI scan.
Do Participants Receive Compensation as Part of the Study:
Yes
What compensation Do Participants Receive:
Compensation is provided. Please contact the study coordinator for more details.


Project Title:
Anhedonia Study
Principal Investigator:
Erika Forbes, Ph.D.
For Information Contact:

Rachel LePage: lepager@upmc.edu; 412-589-9013

What We Are Studying:
We are assessing various levels of anhedonia (the loss of interest or pleasure in daily life and activities) and how it affects brain function over the course of adolescence.
Who Is Eligible to Participate:
Parents with a history of depression, bipolar disorder, or schizophrenia who have a child (target adolescent) between the ages of 13-17 with no history of depression, bipolar disorder, or schizophrenia. To see if you are eligible, follow this link: https://pitt.co1.qualtrics.com/SE/?SID=SV_dcgHy3FloBmfNNb
Who Is Not Eligible to Participate:
The target adolescents may not have a history of depression, bipolar disorder, or schizophrenia.
What Participation Involves:
Parents will complete interviews and questionnaires. Adolescents will complete interviews, questionnaires, computer tasks, and an fMRI scan.
Do Participants Receive Compensation as Part of the Study:
Yes
What compensation Do Participants Receive:
Compensation is provided. Please contact the study coordinator for more details.


Project Title:
PADI Study
Principal Investigator:
Anna Manelis, Ph.D.
For Information Contact:

Tina Liu, Research Associate (Email: padi@upmc.edu; Telephone: 412-383-3110)

What We Are Studying:
We are interested in understanding how the brain works in people with and without mood disorders utilizing fMRI scanning.
Who Is Eligible to Participate:
Individuals between the ages of 18 and 45 that have a history of depression or mania.
Who Is Not Eligible to Participate:
People currently in a manic state.
What Participation Involves:
Participants will have a lifetime psychiatric evaluation and complete self-report questionnaires to determine eligibility at the first visit. During the second visit, the participant will undergo an fMRI scan, complete additional questionnaires, and perform certain cognitive tasks. The fMRI and other tasks are non-invasive.
Do Participants Receive Compensation as Part of the Study:
Yes
What compensation Do Participants Receive:
Participants will receive $10 to $25 for the first visit and $100 for the second visit. Participants will also be reimbursed $10 for transportation at each visit.


Project Title:
A New Statistical Paradigm for Measuring Psychopathology Dimensions in Youth (YCAT Study)
Principal Investigator:
David Brent, MD
For Information Contact:

Brandie George-Milford (Telephone: 412-246-5629 or 412-586-9405; Email: ycat@upmc.edu)

What We Are Studying:
The purpose of the study is to learn more about the assessment of mood and behavior problems in children.
Who Is Eligible to Participate:
Boys and girls 7-17 years old that are in treatment for mood or behavioral problem and their legal guardians/parents.
Who Is Not Eligible to Participate:
Youth with a diagnosis of psychosis or autism are not eligible.
What Participation Involves:
Participation involves one visit, lasting approximately 2 hours, for a youth-parent pair. The visit includes taking the YCAT survey on an iPad and answering between 150-200 questions about health, mood, and behaviors.
Do Participants Receive Compensation as Part of the Study:
Yes
What compensation Do Participants Receive:
Yes, compensation is provided. Please contact the study coordinator for more details.


Project Title:
Ways for Adolescents to Validate Emotions (WAVE): A Therapy Research Study
Principal Investigator:
Tina Goldstein, PhD
For Information Contact:
Megan Krantz, wavestudy@upmc.edu, 412-864-3321

What We Are Studying:
The purpose of this study is to determine the effectiveness of two types of talk therapy (Dialectical Behavior Therapy (DBT) versus Standard of Care (SOC) Psychotherapy) in addition to usual clinical care among adolescents and young adults with Bipolar Disorder.
Who Is Eligible to Participate:
Adolescents with bipolar disorder ages 12-18 and their parents/legal guardians may be eligible to participate.
Who Is Not Eligible to Participate:
Individuals with a diagnosis of autism spectrum disorder or mental retardation are not eligible to participate in this study.
What Participation Involves:
Participating families will be assigned randomly (by chance) to receive either DBT or SOC psychotherapy at the CABS clinic. Adolescents and their family members must be willing to participate regularly in therapy sessions for one year at the CABS outpatient clinic at Bellefield Towers in the Oakland section of Pittsburgh. All adolescent participants will be followed by a CABS physician who administers and monitors the adolescent’s medications. Adolescents and their parents will also take part in regular research interviews (every three months during the first year and every 6 months during the second year) and fill out questionnaires about their symptoms and functioning.
Do Participants Receive Compensation as Part of the Study:
Yes
What compensation Do Participants Receive:
Compensation is provided. Please contact the study coordinator for more details.


Project Title:
Diamond Brain Imaging Study
Principal Investigator:
Mary Phillips, M.D.
For Information Contact:

TEXT: DIAMOND to 412-999-2758; EMAIL: fmristudies@upmc.edu; CALL: 412-383-3109; WEBPAGE: www.diamond.pitt.edu

What We Are Studying:
Using fMRI scan techniques, this study is focusing on differences in emotion and brain functioning in those experiencing severe distress compared to those who are not. No treatment is provided.
Who Is Eligible to Participate:
Young Adults age 18-25 currently experiencing distress severe enough that they have sought treatment. They do not have to meet any disorder but they also are eligible if they do. Matched young adults who have never experienced distress or any psychiatric disorders.
Who Is Not Eligible to Participate:
Those on psychotropic medications for more than a couple weeks (or controls - ever); Those with current alcohol or substance abuse; Those with a history of severe concussion, neurological disorder, metal in the body, having claustrophobia, or currently pregnant.
What Participation Involves:
Participants will have a full clinical evaluation to determine eligibility and then complete self-report questionnaires on the screen day. Following that they will have an fMRI scan where they will complete tasks in the scanner and complete a brief clinical assessment & self-report forms. There is also a blood draw, if the participant agrees. For the distressed group, there are 2 follow-up clinical appointments at 6- and 12- months.
Do Participants Receive Compensation as Part of the Study:
Yes
What compensation Do Participants Receive:
Compensation for participation is as follows: $25 – screen visit; $75 – scan visit with potential to ‘win’ $6 more in the tasks/games in the scanner; $20 – blood draw; and $30 - follow-up visits.