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Project Title:
Cortical Cells, Circuits, Connectivity and Cognition in Psychosis
Principal Investigator:
Beatriz Luna, Ph.D.
For Information Contact:

Kevin Eklund, RN, BSN; eklundkd@upmc.edu; (412) 586-9009 for the first-episode psychosis studies or Alicia Thomas, MS; thomasaa@upmc.edu; (412) 586-9096 for healthy control studies.

What We Are Studying:
We are trying to learn about the causes of psychotic symptoms and are addressing this problem in a number of ways using recently developed methods of studying the structure and functioning of the brain and thinking processes that we believe may be involved. The purpose of this study is to better understand which aspects of brain functioning are affected in psychotic illnesses and whether this changes over time.
Who Is Eligible to Participate:
Males and Females, Ages 14-35: (1) first-episode of psychosis with little/no previous treatment, and (2) healthy controls with no history of a psychiatric disorder.
Who Is Not Eligible to Participate:
Those with certain medical/neurological conditions, mental retardation, pregnant women, substance dependence in the previous six months or abuse (except for alcohol and cannabis) in the previous month are not eligible to participate. Further, healthy controls who have a history of antipsychotic treatment or a first-degree family history of psychosis are not eligible.
What Participation Involves:
Participants will be asked to complete clinical and diagnostic interviews, urine drug screen, neuropsychological assessments, and imaging and electroencephalography (EEG) studies. Diagnosis will be re-assessed at 6 months for individuals experiencing their first episode of psychosis.
Do Participants Receive Compensation as Part of the Study:
Yes
What compensation Do Participants Receive:
Participants may receive up to $225 at baseline and $75 at the 6-month follow-up.


Project Title:
PADI Study
Principal Investigator:
Anna Manelis, Ph.D.
For Information Contact:

Tina Liu, Research Associate (Email: padi@upmc.edu; Telephone: 412-383-3110)

What We Are Studying:
We are interested in understanding how the brain works in people with and without mood disorders utilizing fMRI scanning.
Who Is Eligible to Participate:
Individuals between the ages of 18 and 45 that have a history of depression or mania.
Who Is Not Eligible to Participate:
People currently in a manic state.
What Participation Involves:
Participants will have a lifetime psychiatric evaluation and complete self-report questionnaires to determine eligibility at the first visit. During the second visit, the participant will undergo an fMRI scan, complete additional questionnaires, and perform certain cognitive tasks. The fMRI and other tasks are non-invasive.
Do Participants Receive Compensation as Part of the Study:
Yes
What compensation Do Participants Receive:
Participants will receive $10 to $25 for the first visit and $100 for the second visit. Participants will also be reimbursed $10 for transportation at each visit.


Project Title:
Psychobiology of Suicidal Behavior in Borderline Personality Disorder
Principal Investigator:
Paul H. Soloff, MD
For Information Contact:

Mary Jones; jonesm@upmc.edu; (412) 246-5367

What We Are Studying:
Participants are interviewed about their moods, behaviors, and personality traits related to borderline personality disorder.
Who Is Eligible to Participate:
Individuals ages 18-45, who have experienced symptoms of borderline personality disorder, such as: troubled personal relationships, chronic feelings of emptiness or boredom, difficulty controlling anger or frustration, mood swings, self-destructive or impulsive behaviors, or history of self-inflicted pain or injury.
Who Is Not Eligible to Participate:
Individuals with current or lifetime DSM-IV defined psychotic disorder (such as, schizophrenia, schizoaffective disorder, delusional disorder), Bipolar disorder, and IQ < 70. The following are exclusions for the fMRI portion of the study only: 1) ferro-magnetic implants such as cardiac pacers, cochlear implants, aneurysm clips, history of metal in eyes or other ferromagnetic body artifacts; 2) inability to fit in the scanner; 3) claustrophobia or inability to tolerate brief confinement in the scanner; 4) pregnancy.
What Participation Involves:
After completion of a telephone screen to determine eligibility, subjects complete a series of diagnostic screening interviews. Upon completion of these, if they make it into the study, they are scheduled for a baseline assessment, and if they wish to participate, an optional fMRI scan.
Do Participants Receive Compensation as Part of the Study:
Yes
What compensation Do Participants Receive:
Subjects are compensated $25 for each of the three diagnostic interviews, and $50 for the baseline interview. They are also compensated $50 for the one hour fMRI scan (for a potential total of $175).


Project Title:
Emotion & Physiology Assessment Study (EPAS)
Principal Investigator:
Greg Siegle, Ph.D.
For Information Contact:

Amanda L. Collier, B.S., Lead Research Project Coordinator. 412-383-5448, collieral@upmc.edu, Loeffler Bldg, room 230, 121 Meyran Ave.

What We Are Studying:
We are doing this to examine brain and physiological reactions to emotional information. We are particularly interested in how the brain regulates reactions to stimuli that are usually considered emotional, such as pictures, words, sounds, and stories.
Who Is Eligible to Participate:
Native English speaking adults 18-58 years old who are able to undergo fMRI scanning and are currently depressed, or anxious, but preferably meeting criteria for Post Traumatic Stress Disorder (PTSD) or Borderline Personality Disorder (BPD).
Who Is Not Eligible to Participate:
People with history of severe head trauma, stroke, seizures, vision or hearing problems, contraindications for fMRI, current or historical bipolar I, psychotic disorders, or current substance dependence.
What Participation Involves:
Participants will be asked to complete a series of four visits at UPMC facilities in Oakland including the MRI Research Center in Presbyterian Hospital. On the first two days, we will do interviews to assess one’s well-being and mental health history, and ask participants to complete some forms. These visits will last approximately 3 hours each. On the third visit participants will complete some tasks at a computer while we record their eye position, pupil dilation, breathing, heart rate, brain waves, and more. This visit lasts approximately 3-4 hours. Finally, on the fourth visit, which is 3.5 hours long, participants do a one-and-a-half-hour fMRI and complete some forms.
Do Participants Receive Compensation as Part of the Study:
Yes
What compensation Do Participants Receive:
Up to $350 for full participation. Compensated up to $60 for each interview visit (or $20/hour up to 3 hours for screen outs. The lab and scan visits pay $100 each and there are opportunities for on time and task bonuses.


Project Title:
Neural and Social Processes of Positive Affect in Children at Risk for Depression
Principal Investigator:
Judith Morgan, PhD
For Information Contact:

Catherine Venable; pittcarelab@gmail.com; (412) 624-7991

What We Are Studying:
Reward-related processing in young children at familial risk for depression.
Who Is Eligible to Participate:
Biological mothers with or without a history of depression and their 6 to 8 year old emotionally healthy children.
Who Is Not Eligible to Participate:
Mothers with a history of Bipolar Disorder or Psychosis. Children with psychiatric illnesses or developmental delays.
What Participation Involves:
Visit 1: 3 hour laboratory visit (includes clinical interviews, questionnaires, and child behavioral tasks). Visit 2: 90 minute laboratory visit (includes an fMRI scan for the child).
Do Participants Receive Compensation as Part of the Study:
Yes
What compensation Do Participants Receive:
Compensation is provided. Please contact Catherine Venable for more details.


Project Title:
Neural Dimensions of Attention Bias Modification for Transdiagnostic Anxiety
Principal Investigator:
Rebecca Price, PhD
For Information Contact:

Logan Cummings, cummingslr3@upmc.edu, 412-624-5541

What We Are Studying:
This study examines a new computer-based intervention designed to reduce anxiety. The study also examines how the brain functions in anxious individuals.
Who Is Eligible to Participate:
Individuals age 18-55 with clinically significant anxiety.
Who Is Not Eligible to Participate:
Individuals currently taking antidepressant or anti-anxiety medications.
What Participation Involves:
Over a 1-month period, participants will complete a clinical interview, questionnaires, an fMRI brain scan, and repeated practice on a computer-based task.
Do Participants Receive Compensation as Part of the Study:
Yes
What compensation Do Participants Receive:
Compensation of up to $270 is provided upon completion of study.


Project Title:
STOP PD II (Sustaining Remission of Severe Depression II)
Principal Investigator:
Ellen Whyte, MD
For Information Contact:

Joelle Scanlon, PhD; Email: scanjm2@upmc.edu; Telephone: 412-246-6012

What We Are Studying:
Most of us have heard of depression, but few people may know about a type of depression that appears along with psychosis (or a loss of touch with reality). Referred to as psychotic major depression (PMD), it’s a surprisingly common mental disorder that affects more than one in 100 individuals. Researchers know that combination treatment (using both an antipsychotic + antidepressant) is needed when using medication to treat severe depression with psychosis. Now, researchers are working to understand how long people need to stay on an antipsychotic medication to prevent new episodes of psychosis after recovering from their initial symptoms.
Who Is Eligible to Participate:
Individuals, ages 18 to 85 years old, who experience the following symptoms: Persistently sad mood, feelings of hopelessness/pessimism, irritability/restlessness, poor sleep, feelings of guilt or worthlessness, poor concentration or memory problems, fatigue or poor energy, thoughts of suicide or suicide attempts, severe, distressing worries, hearing/seeing things that are bizarre or improbable, ideas or ways of thinking that are not true. Participation can begin in an inpatient or outpatient setting.
Who Is Not Eligible to Participate:
Individuals with current/lifetime DSM-IV defined psychotic disorder (e.g., schizophrenia, schizoaffective disorder, delusional disorder), Bipolar disorder, current DSM-IV defined OCD or Body Dysmorphic Disorder, DSM-IV defined substance abuse/dependence within the last 3 months, current diagnosis of dementia/significant premorbid cognitive impairment, Type I diabetes Mellitus, Pregnancy or plan to become pregnant, Medical instability
What Participation Involves:
First, participants will undergo a complete psychiatric and medical assessment, including a physical exam and blood tests, to make sure that the study medications are appropriate and safe for the individual. Individuals who are eligible to participate in Phase I will receive a combination of an antidepressant (Zoloft) and an antipsychotic (Zyprexa) for up to 20 weeks. If the participant responds to these medications, he/she will have the option of entering Phase 2, during which the participant will either continue with Zoloft + Zyprexa, or receive Zoloft + Placebo, for up to 36 weeks. The participant’s mood and overall health will be assessed frequently throughout the study. Study participants receive medication and medical care at no cost.
Do Participants Receive Compensation as Part of the Study:
Yes
What compensation Do Participants Receive:
$10 for Phase 1 research visits, $20 for Phase 2 research visits, Assistance with transportation if needed.


Project Title:
Diamond Brain Imaging Study
Principal Investigator:
Mary Phillips, M.D.
For Information Contact:

TEXT: DIAMOND to 412-999-2758; EMAIL: fmristudies@upmc.edu; CALL: 412-383-3109; WEBPAGE: www.diamond.pitt.edu

What We Are Studying:
Using fMRI scan techniques, this study is focusing on differences in emotion and brain functioning in those experiencing severe distress compared to those who are not. No treatment is provided.
Who Is Eligible to Participate:
Young Adults age 18-25 currently experiencing distress severe enough that they have sought treatment. They do not have to meet any disorder but they also are eligible if they do. Matched young adults who have never experienced distress or any psychiatric disorders.
Who Is Not Eligible to Participate:
Those on psychotropic medications for more than a couple weeks (or controls - ever); Those with current alcohol or substance abuse; Those with a history of severe concussion, neurological disorder, metal in the body, having claustrophobia, or currently pregnant.
What Participation Involves:
Participants will have a full clinical evaluation to determine eligibility and then complete self-report questionnaires on the screen day. Following that they will have an fMRI scan where they will complete tasks in the scanner and complete a brief clinical assessment & self-report forms. There is also a blood draw, if the participant agrees. For the distressed group, there are 2 follow-up clinical appointments at 6- and 12- months.
Do Participants Receive Compensation as Part of the Study:
Yes
What compensation Do Participants Receive:
Compensation for participation is as follows: $25 – screen visit; $75 – scan visit with potential to ‘win’ $6 more in the tasks/games in the scanner; $20 – blood draw; and $30 - follow-up visits.


Project Title:
Elucidating the Neural Circuitry of OCD to Improve Real-Life Experiences (ENCORE)
Principal Investigator:
Mary Phillips, M.D.
For Information Contact:

Simona Graur; graurs@upmc.edu; (412) 256-8693

What We Are Studying:
Characterizing abnormalities in the OCD neural network
Who Is Eligible to Participate:
Persons between the ages of 18 and 35 that have symptoms of OCD (OCD group). Persons between the ages of 18 and 35 that have no history of psychiatric disorders (Control Group).
Who Is Not Eligible to Participate:
Participants are not eligible if they are not between 18-35 years old, have a systemic medical disease, have a history in the last 3 months of illicit substance abuse/dependence, are left/mixed handed, pregnant, prone to panicking in enclosed spaces, have metallic objects in their bodies, have psychotic symptoms, have history of head injury, currently suicidal, or have a personal/family history of any of the following: neurodevelopmental disorder, schizophrenia and/or schizoaffective disorder, primary psychotic disorder, bipolar disorder, present PTSD, present depressive episode. In addition, OCD participants must not have taken in excess of one selective serotonin reuptake inhibitor (SRI) antidepressant medication or clomipramine within the previous 3 months.
What Participation Involves:
Participants will have a lifetime psychiatric evaluation and complete various tasks while having an fMRI (Functional Magnetic Resonance Imaging) scan. The fMRI and other tasks are non-invasive procedures.
Do Participants Receive Compensation as Part of the Study:
Yes
What compensation Do Participants Receive:
$25 for psychiatric evaluation and $80 for the fMRI portion.


Project Title:
Autism Parent Child Interaction Therapy Project (PCIT)
Principal Investigator:
Benjamin Handen, Ph.D.
For Information Contact:

Jodi Toscolani, M.Ed. (Email: toscolanijm@upmc.edu; Telephone: 412-235-5405)

What We Are Studying:
The purpose of this study is to examine the effectiveness of Parent Child Interaction Therapy (PCIT). PCIT involves working directly with the parent and their children to teach specific skills related to play and learning how to follow adult requests.
Who Is Eligible to Participate:
Male and female; children 2.6 to 6.11 years of age; Have a diagnosis of Autism Spectrum Disorder; Difficulty following adult requests.
Who Is Not Eligible to Participate:
Unstable use of psychotropic medications or dietary supplements; prior involvement with PCIT or current parent training; extreme severe behavioral concerns.
What Participation Involves:
16 week sessions
Do Participants Receive Compensation as Part of the Study:
Yes
What compensation Do Participants Receive:
Contact the project coordinator for details.


Project Title:
Decision Processes of Late-Life Suicide
Principal Investigator:
Katalin Szanto, M.D.
For Information Contact:
Laura Kenneally (kenneallylb@upmc.edu; Telephone: (412) 802-8463)

What We Are Studying:
We are interested in understanding why some middle-aged and older adults become depressed, contemplate suicide and/or try to end their lives.
Who Is Eligible to Participate:
Participants may be eligible if they are between the ages of 50 and 85 and are either currently depressed OR if they have no psychiatric history.
Who Is Not Eligible to Participate:
Participants are not eligible if they have any history of neurological disorder, dementia, bipolar disorder, or psychotic disorder, if they have had any ECT treatment within the last 6 months, or if they have any history of stroke.
What Participation Involves:
Participants will complete a baseline appointment, including clinical assessments, decision-making games, and memory testing. Participants will then complete a shorter, annual follow-up visit once a year for up to 4 years. Participants will also complete an fMRI, if eligible.
Do Participants Receive Compensation as Part of the Study:
Yes
What compensation Do Participants Receive:
Compensation is provided. Eligible participants will receive between $75 and $130 for the initial appointment, and $50 for each annual visit. Reimbursement for parking and transportation is also available.


Project Title:
ASSET Study (Adolescents’ Social Stresses, Emotions, and Thoughts)
Principal Investigator:
Leslie Horton, PhD
For Information Contact:
Aaron Hein (412-624-7778, assetstudy@upmc.edu), Or text the word “teenager” to (412)-999-2748

What We Are Studying:
We are studying the social stresses, emotions, and thoughts of teens, both those with and without a parent with a diagnosis of schizophrenia or schizoaffective disorder.
Who Is Eligible to Participate:
Teenagers age 14-17 and their parent; Parent has a schizophrenia/schizoaffective disorder diagnosis
Who Is Not Eligible to Participate:
Teenagers of history of head trauma with loss of consciousness; Teenagers who themselves have a current diagnosis of schizophrenia / psychotic disorder; Teenagers taking certain medications (benzodiazepines, stimulants, antipsychotics); Teenagers unwilling to abstain from nicotine and caffeine on the day of testing
What Participation Involves:
We will examine social stresses, emotions, and thoughts 3 times over 1 year. Activities will include interviews, computer tasks, those in the laboratory (for example, looking at heart rate responses to stressful tasks), and in daily life (loaning participants a cell phone with an application that randomly beeps and asks questions about current experiences).
Do Participants Receive Compensation as Part of the Study:
Yes
What compensation Do Participants Receive:
Parent participants will be compensated $50 (1 study visit). Please contact study coordinator for additional details.


Project Title:
Mismatch Negativity and Complex Second-Order Sensory Memory in Schizophrenia
Principal Investigator:
Dean Salisbury, PhD
For Information Contact:

Individuals with Schizophrenia please contact Kevin Eklund, RN, Email: EklundKD@upmc.edu, Telephone: (412) 586-9009
Individuals who do not have Schizophrenia please call the CNRL lab phone number, Telephone: (412) 246-6533

What We Are Studying:
This study seeks to understand more about auditory perceptual and memory problems in psychosis by studying (1) individuals who have just developed symptoms for the first time and have little or no treatment for the symptoms, (2) those with chronic schizophrenia, and (3) healthy individuals with no mental health problems.
Who Is Eligible to Participate:
Males and Females, Ages 18-55, who either: (1) have received treatment for the first time in the past 2 months for psychosis; (2) have a diagnosis of schizophrenia AND have had at least 3 hospitalizations for psychosis; or (3) healthy individuals with no history of mental health problems.
Who Is Not Eligible to Participate:
Those with a history of a diagnosed learning disorder, previous treatment for childhood ADHD, neurological disorder (like seizures) or severe head injury, drug/alcohol dependence. Certain medical illnesses may also exclude individuals from participating.
What Participation Involves:
A screening interview will determine eligibility. Those eligible will complete an EEG session, in which they will hear series of different sounds while watching a silent movie and having their brainwaves recorded to measure sensory memory. Participants will also complete clinical interviews and neuropsychological testing. Approximate time to completion can be up to 10 hours.
Do Participants Receive Compensation as Part of the Study:
Yes
What compensation Do Participants Receive:
Individuals may receive up to $150 for successful completion of the study.


Project Title:
Puberty, Emotions, and the Brain
Principal Investigator:
Cecile Ladouceur, PhD
For Information Contact:

Claire Dempsey; dempseycm@upmc.edu; (412) 383-8134; Eunice Matela; mateae@upmc.edu; (412) 383-8134; Study email; pebs@pitt.edu

What We Are Studying:
We are studying the effects of puberty on adolescent brain development and vulnerability to affective disorders.
Who Is Eligible to Participate:
Females ages 10-12 years old and males ages 11-13 years old.
Who Is Not Eligible to Participate:
Children with metal in their bodies (e.g. plates, braces); children with diagnosed mental health disorders; children with left-handedness; and pregnant females.
What Participation Involves:
Participation involves visiting our lab with a parent and completing computer games while we take pictures of your brain. Mental and physical assessments will also be completed.
Do Participants Receive Compensation as Part of the Study:
Yes
What compensation Do Participants Receive:
Compensation is provided. Please contact the study coordinator for more details.


Project Title:
Improving Access to Care via mHealth Technology
Principal Investigator:
Oliver Lindhiem, Ph.D.
For Information Contact:

Charles Bennett (Email: bennettcb@upmc.edu; Telephone: 412-246-5901)

What We Are Studying:
The purpose of this study is to test a smartphone app that is designed to help parents and children manage mild to moderate behavior problems.
Who Is Eligible to Participate:
Parents and children (ages 8-12) with mild to moderate behavior problems and access to a computer with internet connection.
Who Is Not Eligible to Participate:
Families with: a) Children 7 years or younger; b) Children 13 years or younger; c) No access to internet; d) Serious psychopathology requiring alternative treatment or families receiving parallel services.
What Participation Involves:
Participants will be randomly assigned to one of two groups: a group that begins using the app immediately after the initial assessment or a wait list group that will wait for 4 months before beginning to use the app. Each group will be asked to complete a series of assessments online. All but one assessment will be completed online. Participants will also be asked to travel to the office to learn how to use the app. Participation will last up to 7 months for the treatment group and 11 months for the wait-list control group. Participants will be asked to complete a set of assessments right before they begin using the app, and then again 4 months later and at 7 months later.
Do Participants Receive Compensation as Part of the Study:
Yes
What compensation Do Participants Receive:
Participants will be compensated up to $150 ($75 for parent and $75 for child) if they are assigned to the group that immediately receives the app. Participants will be compensated up to $200 ($100 for parent and $100 for child) if they are assigned to the wait-list group.


Project Title:
Ways for Adolescents to Validate Emotions (WAVE): A Therapy Research Study
Principal Investigator:
Tina Goldstein, PhD
For Information Contact:
Megan Krantz, wavestudy@upmc.edu, 412-864-3321

What We Are Studying:
The purpose of this study is to determine the effectiveness of two types of talk therapy (Dialectical Behavior Therapy (DBT) versus Standard of Care (SOC) Psychotherapy) in addition to usual clinical care among adolescents and young adults with Bipolar Disorder.
Who Is Eligible to Participate:
Adolescents with bipolar disorder ages 12-18 and their parents/legal guardians may be eligible to participate.
Who Is Not Eligible to Participate:
Individuals with a diagnosis of autism spectrum disorder or mental retardation are not eligible to participate in this study.
What Participation Involves:
Participating families will be assigned randomly (by chance) to receive either DBT or SOC psychotherapy at the CABS clinic. Adolescents and their family members must be willing to participate regularly in therapy sessions for one year at the CABS outpatient clinic at Bellefield Towers in the Oakland section of Pittsburgh. All adolescent participants will be followed by a CABS physician who administers and monitors the adolescent’s medications. Adolescents and their parents will also take part in regular research interviews (every three months during the first year and every 6 months during the second year) and fill out questionnaires about their symptoms and functioning.
Do Participants Receive Compensation as Part of the Study:
Yes
What compensation Do Participants Receive:
Compensation is provided. Please contact the study coordinator for more details.


Project Title:
The Couples Study
Principal Investigator:
Paul Pilkonis, Ph.D.
For Information Contact:

Kristen Cushman, cushmank@upmc.edu 412-246-6517

What We Are Studying:
We are interested in the associations between personality traits, emotions, and how individuals interact with people close to them. We are also interested in the experience of being in a relationship with someone receiving mental health care.
Who Is Eligible to Participate:
Couples who are currently involved in a romantic relationship for at least a month may be eligible. One person in the couple must be currently receiving mental health treatment and be between the ages of 18 and 40 years old.
Who Is Not Eligible to Participate:
Individuals who are not currently in a romantic relationship, individuals who are not in the age range, and individuals with traumatic brain injuries, strokes, or other major problems of the central nervous system.
What Participation Involves:
Both members of the couple participate, but the information they provide is not shared between them. Participants will complete a series of questionnaires and interviews asking about their past and current mental health treatment; the nature and quality of their relationships with their romantic partner, family, and friends; and how they react in certain situations. Participants will also be asked to complete a computer task and to tell us about their day-to-day lives using smart phones. One task is completed with both people together – a discussion in our office. Some tasks are repeated at different times over a one-year period.
Do Participants Receive Compensation as Part of the Study:
Yes
What compensation Do Participants Receive:
Participants will each receive $25 to $50 for every visit, with maximum compensation that could amount to $805 per person over an entire year.


Project Title:
MS Heart Study
Principal Investigator:
Rebecca Thurston, Ph.D.
For Information Contact:

Shannon Nichter: 412-624-2016 OR Dana Schreiber: 412-648-7096; Email: msheartstudy@gmail.com

What We Are Studying:
The study is designed to better understand the development of cardiovascular risk in midlife women.
Who Is Eligible to Participate:
Healthy volunteers, women, non-smoking, no known cardiovascular disease, not taking hormones, cardiac medications, insulin or antidepressants. No history of hysterectomy or removal of ovaries. Women with no hot flashes or daily hot flashes may be eligible.
Who Is Not Eligible to Participate:
Men, women under age 40 or over age 60, currently smoking or using tobacco products, women who had had a hysterectomy or bilateral oophorectomy, or are currently pregnant. Women using taking hormones, antidepressants or undergoing chemotherapy currently or in the last three months. Women undergoing treatment for cardiovascular disease, using insulin for the treatment of diabetes, or with a history of stroke.
What Participation Involves:
Participation includes wearing monitors that measure heart rate, hot flashes, and sleep as you go about your daily activities. Study procedures also include ultrasound images of your blood vessels and one fasting blood draw.
Do Participants Receive Compensation as Part of the Study:
Yes
What compensation Do Participants Receive:
Participants are eligible to receive $150 compensation. Study also provides compensation for bus fares and parking fees for lab visits.


Project Title:
A New Statistical Paradigm for Measuring Psychopathology Dimensions in Youth (YCAT Study)
Principal Investigator:
David Brent, MD
For Information Contact:

Brandie George-Milford (Telephone: 412-246-5629 or 412-586-9405; Email: ycat@upmc.edu)

What We Are Studying:
The purpose of the study is to learn more about the assessment of mood and behavior problems in children.
Who Is Eligible to Participate:
Boys and girls 7-17 years old that are in treatment for mood or behavioral problem and their legal guardians/parents.
Who Is Not Eligible to Participate:
Youth with a diagnosis of psychosis or autism are not eligible.
What Participation Involves:
Participation involves one visit, lasting approximately 2 hours, for a youth-parent pair. The visit includes taking the YCAT survey on an iPad and answering between 150-200 questions about health, mood, and behaviors.
Do Participants Receive Compensation as Part of the Study:
Yes
What compensation Do Participants Receive:
Yes, compensation is provided. Please contact the study coordinator for more details.


Project Title:
Emotion Regulation in Depression
Principal Investigator:
Jay Fournier, PhD
For Information Contact:

Logan Cummings, cummingslr3@upmc.edu, 412-624-5541, or by texting FMINDS to 412-999-2758

What We Are Studying:
We will be using functional magnetic resonance imaging (or fMRI) to take pictures of your brain while you view different types of pictures, words, or sentences on a computer screen. We will compare fMRI scans from people with depression to those scans from people with no disorders. This will help to improve our understanding of the way the brain works in people who have depression.
Who Is Eligible to Participate:
Individual that are: 1) Aged 18-40; 2) Currently depressed OR who have no history of psychiatric disorders and 3) Must be right handed.
Who Is Not Eligible to Participate:
1) Individuals diagnosed with bipolar disorder, schizophrenia, or an active alcohol or substance use disorder; 2) Individuals currently receiving psychiatric medication or psychotherapy and 3) Individuals with a history of head trauma.
What Participation Involves:
There are two visits involved in this study. The first will involve interviews and questionnaires. During the second visit, participants will undergo an fMRI scan and complete additional questionnaires.
Do Participants Receive Compensation as Part of the Study:
Yes
What compensation Do Participants Receive:
Participants will be compensated up to $110 for completing both visits ($25 for the first visit, $85 for the second visit). The study will provide vouchers for bus fare or parking passes at study approved lots.