Become a Research Participant
Project Title:
Randomized Clinical Trial of a Novel Psychotherapy for Childhood Depression (CERT)
Principal Investigator:
Maria Kovacs, Ph.D.
For Information Contact:
Heather Dukes-Murray, Ph.D. at murrayh@pitt.edu or 412-246-5700
What We Are Studying:
We are studying how our new version of talk therapy (CERT) compares with an established therapy (CCT) in helping children with depression.
Who Is Eligible to Participate:
Boys and girls between the ages of 7-12 with a depression diagnosis or concerns about possible depression. Children diagnosed with additional anxiety and behavioral disorders (e.g., ADHD) are eligible. Children already on medication are welcome.
Who Is Not Eligible to Participate:
Boys and girls diagnosed with Mental Retardation, Psychotic Disorder, Bipolar Disorder, Obsessive-Compulsive Disorder, or Autism Spectrum Disorder are not eligible.
What Participation Involves:
Participants will be asked to take part in an initial evaluation. If eligible, they will be randomly assigned to Contextual Emotion Regulation Therapy (CERT), an age-sensitive, skills-focused talk therapy, or Client-Centered Therapy, a relationship-focused talk therapy. Children will take part in 6 months of therapy. At the conclusion of therapy, they will complete another evaluation. Participants will complete follow-up evaluations 6 months and 1 year after therapy is completed in order to track long-term benefits.
Do Participants Receive Compensation as Part of the Study:
Yes
What compensation Do Participants Receive:
Participants are compensated for all evaluations. Participants are paid $60 for the intake evaluation and the evaluation completed at the conclusion of the 6 months of therapy. Participants are paid $125 for each of the follow-up evaluations occurring 6 months and 1 year after therapy has ended. Our study can also assist families with childcare during sessions and with transportation.
Project Title:
Aging Well, Sleeping Efficiently (AgeWise) Study
Principal Investigator:
Timothy Monk, Ph.D., D.Sc.
For Information Contact:
Call toll free 1-866-647-8283 or Laurie Brar, CRNP, MSN at brarlk@upmc.edu or 412-246-6445
What We Are Studying:
Brain function in older adults with and without insomnia, and the changes in brain function that occur after a behavioral treatment of the insomnia. The research covers several different domains, including brain electrical activity (EEG), 24-hour biological rhythms, reactions to stress, imaging of brain function, and genetics related to sleep
Who Is Eligible to Participate:
Men and women age 60 and older who have had chronic insomnia for at least 6 months, characterized by and difficulty staying asleep. Participants must be in stable medical condition; have no history of a neurologic disorder or stroke, not be taking medications for sleep or depression, and not have been diagnosed with or treated for sleep apnea. Good-sleeping older adults meeting similar criteria will also be recruited (see below).
Who Is Not Eligible to Participate:
Men and women under 60 years of age; history of neurologic disorder or stroke, taking medications for sleep or depression, diagnosed or treated for sleep apnea. Certain other exclusionary criteria (e.g., metal in the body) also apply to specific laboratory evaluations.
What Participation Involves:
Those who are eligible for the study will be given a detailed health and sleep screening. If they pass that screening, they will then participate in one of three different laboratory evaluations, each lasting several days, which will be conducted twice: Once before, and once after behavioral treatment for insomnia. These evaluations will be supplemented by data obtained from diaries, questionnaires and interviews.
Do Participants Receive Compensation as Part of the Study:
Yes
What compensation Do Participants Receive:
Participants are compensated between $500 and $600 depending upon the laboratory evaluation to which they are assigned. We are also recruiting good sleeping seniors meeting similar criteria. Good sleeping seniors only participate once in the laboratory evaluation and do not receive treatment. They are compensated between $250 and $300 depending upon the laboratory evaluation to which they are assigned.
Project Title:
Light Therapy for Bipolar Disorder
Principal Investigator:
Dorothy Sit, M.D.
For Information Contact:
Jonathan Weingarden at weingardenj@upmc.edu, 412-246-5346 or 1-800-436-2461
What We Are Studying:
The efficacy of add-on light therapy for patients with a current episode of Bipolar Depression.
Who Is Eligible to Participate:
1) Men OR Women; 2) Ages 18-65; 3) Bipolar Disorder, Type I or Type II; 4) Current Episode of Major Depression; and 5) Current Mood Stabilizer Treatment (like Lithium, Depakote, Tegretol. risperidone, quetiapine etc). Additional Eligibility Criteria will apply.
Who Is Not Eligible to Participate:
1) Current Hypomania, Mania, Mixed Episode, any Psychotic Symptoms; 2) Rapid Cycling; 3) Alcohol Abuse or Dependence no or in the last 6 months; 4) Substance Abuse or Dependence (Marijuana, Cocaine, Heroin, Pain Meds, Methadone) now or in the last 6 months; 5) Antidepressant Monotherapy; 6) No Mood Stabilizer Treatment; 7) Uses a light box now or has used a light box in the past. Additional Exclusion Criteria will apply.
What Participation Involves:
Randomization to active or inactive light treatment intervention for 6-24 weeks. Weekly monitoring of mood and adverse effects for 6 weeks during the acute phase. Regular feedback on treatment response. After 6 weeks: * Treatment non-responders will be informed of their assigned treatment and provided consultation on other effective treatment options for Bipolar Depression. * Treatment responders will continue the assigned light intervention for another 18 weeks (max of 24 weeks in the study). * At the final visit, responders will be informed about their assigned treatment and provided treatment options based on their response.
Do Participants Receive Compensation as Part of the Study:
Yes
What compensation Do Participants Receive:
Participants receive $20.00 compensation for office study visits.
Project Title:
Child Anxiety Treatment Study (CATS)
Principal Investigator:
Neal Ryan, M.D.
For Information Contact:
Sherri Karas, MEd at scheboths@upmc.edu or 412-383-8182; http://www.wpic.pitt.edu/research/CATS/
What We Are Studying:
The purpose of this research project is to study how talking therapy influences children and adolescents with anxiety disorders
Who Is Eligible to Participate:
Any child between the age of 9-13 yrs old who has frequent anxiety, worry or fears (including: excessive daily worry, trouble separating from caregiver, or fear of social situations)
Who Is Not Eligible to Participate:
Any child who is currently using psychiatric medication, risk of harming self or others, or has any non-removable metal (braces, permanent orthodontic devises)
What Participation Involves:
The CATStudy consists of 3 pre-assessment visits followed by 16 weeks of talk therapy. At the conclusion of therapy, participants complete 3 post-assessment visits. There is also a 1 yr and 2 yr follow up visit.
Do Participants Receive Compensation as Part of the Study:
Yes
What compensation Do Participants Receive:
Please call the project coordinator for details.
Project Title:
PASS Study for Youth Depression
Principal Investigator:
Dana McMakin, Ph.D.
For Information Contact:
Candice Croft; Telephone: 412-383-5190; Email: croftcm@upmc.edu.
What We Are Studying:
The purpose of this research study is to develop non-medication treatment approaches for youth depression that are informed by new research in emotion, motivation, and brain development in adolescence. The long-term goal of this study is to decrease lifetime impairments from these common disorders in youth.
Who Is Eligible to Participate:
Males and females between the ages of 12 to 16 years old who are depressed and not currently in talk therapy, and who do not have metal devices such as dental braces (dental fillings are okay), metal plates, pacemakers, etc. in their body may be eligible to participate.
Who Is Not Eligible to Participate:
Individuals ineligible to participate are youth with metal objects or devices in the body, such as dental braces, metal plates, or pacemakers, etc. Dental fillings are allowed.
What Participation Involves:
Participation involves an assessment of symptoms, as well as 6 one-on-one intervention sessions from highly trained professional clinicians at no cost. All participants will complete interviews, online questionnaires, computer tasks, and functional Magnetic Resonance Imaging (fMRI scans involve a magnet taking pictures of the blood flow in the youth’s brain and are painless).
Do Participants Receive Compensation as Part of the Study:
Yes
What compensation Do Participants Receive:
Participants will be compensated for taking part in study and the cost of parking to participate in the project is provided. Please contact the project coordinator for details.
Project Title:
Enhancing Mental Health Treatment Engagement and Retention for Older Adults with Depression (ENGAGED)
Principal Investigator:
Kyaien Conner, Ph.D., M.P.H., L.S.W.
For Information Contact:
Chris Ward; Email: wardcj@upmc.edu; Telephone: 412-383-5188
What We Are Studying:
The goal of this project is to help persons currently experiencing depressive symptoms to learn more about this medical illness and how it can be treated. We hope that the knowledge gained from this study will help to improve our understanding of knowledge and attitudes about depression and its treatment, so that we can develop effective strategies for engaging older adults in depression treatment. In this research study, we will examine the impact of social support, and education about depression provided by a trained ‘Peer Educator’ on attitudes toward depression and treatment, and treatment-related behaviors.
Who Is Eligible to Participate:
We are seeking to enroll individuals aged 60 years and older who may be having some symptoms of depression in this research study.
Who Is Not Eligible to Participate:
People under the age of 60 years and who are not suffering from symptoms of depression, sadness, or anxiety are not eligible to participate. Also, due to the talk therapy offered to participants in the study, incoming participants who are currently enrolled in talk therapy with a personal clinician would not be eligible for this study.
What Participation Involves:
If you are interested in this research study, you will be asked a series of questions about your mood, sleep, appetite, energy level, and your ability to get things done at home, school, or work. Your answers to these questions will help us to determine whether you are eligible to participate in this study. This initial screening will take approximately one hour. If you are eligible for participation, you will be asked a series of questions about emotional symptoms you may be experiencing, what you know about depression and your attitudes toward mental health treatment at your baseline interview. During this interview you will be asked a series of questions about depression and its treatment; this should take approximately two hours. You will complete the same series of questions at three months, six months, nine months, and twelve months. Each interview will take approximately one hour. You will be asked to meet with someone close to your own age (Peer Educator) who will be able to provide you with information about depression and its treatment. The Peer Educator will contact you a few times to talk to you about your experiences and to answer any questions you may have about depression and seeking treatment. Peer Educators will meet with you at least three times over a three month period. Sessions will be a minimum of ten minutes and a maximum of two hours and will take place where you feel most comfortable. Peer Educators are mobile.
Do Participants Receive Compensation as Part of the Study:
Yes
What compensation Do Participants Receive:
Participants in the research study receive $25 each time they complete a series of questionnaires with the Project Coordinator (interviews occur at baseline, three months, six months, nine months, and twelve months).
Project Title:
Acute Psychotherapy for Bipolar II Disorder
Principal Investigator:
Holly Swartz, M.D.
For Information Contact:
Please contact Joan Buttenfield at buttenfieldja@upmc.edu; or by telephone at (412) 246-5588.
What We Are Studying:
We are conducting research to understand whether an experimental psychotherapy is effective in patients with Bipolar II depression when it is given with, or without, a medication.
Who Is Eligible to Participate:
Men and women, ages 18 to 65, who have a diagnosis of Bipolar II Disorder, currently depressed.
Who Is Not Eligible to Participate:
Severe or poorly controlled concurrent medical disorders, presence of any psychotic or organic mental disorder, bipolar I disorder, current alcohol or drug dependence, primary OCD, primary eating disorders, borderline personality disorder or antisocial personality disorder, acute suicidal or homicidal ideation or requiring psychiatric hospitalization, prior lack of response to at least 6 weeks of 300 mg of quetiapine.
What Participation Involves:
Participants will receive up to 20 weeks of treatment that consists of Interpersonal Social Rhythm Therapy for Bipolar Depression and be randomized to receive either the medication Seroquel (quetiapine) or a placebo and have follow-up assessments at 36 and 52 weeks. Patients will receive a psychiatric evaluation, medical evaluation that may include a physical examination, laboratory tests and visits with a study psychotherapist and psychiatrist at no cost.
Do Participants Receive Compensation as Part of the Study:
Yes
What compensation Do Participants Receive:
Participants are compensated $40 at entry, $20 each for assessments at weeks 8, and 12, $30 each for assessments at weeks 20, 36, and 52 (total of $170). Travel reimbursement with either parking vouchers or bus tickets. Food vouchers may also be provided for UPMC dining services during other lengthy research appointments.
Project Title:
Neural Dimensions of Attention Bias Modification for Transdiagnostic Anxiety
Principal Investigator:
Rebecca Price, PhD
For Information Contact:
Danielle Gilchrist, gilchristd@upmc.edu, 412-624-5541
What We Are Studying:
This study examines a new computer-based intervention designed to reduce anxiety. The study also examines how the brain functions in anxious individuals.
Who Is Eligible to Participate:
Individuals age 18-55 with clinically significant anxiety.
Who Is Not Eligible to Participate:
Individuals currently taking antidepressant or anti-anxiety medications.
What Participation Involves:
Over a 1-month period, participants will complete a clinical interview, questionnaires, an fMRI brain scan, and repeated practice on a computer-based task.
Do Participants Receive Compensation as Part of the Study:
Yes
What compensation Do Participants Receive:
Compensation of up to $145 is provided upon completion of study.
Project Title:
Self-Regulation of Rewards in Adolescents
Principal Investigator:
Erika Forbes, Ph.D.
For Information Contact:
Marigrace Ambrosia (412) 383-5439; Email: ambrosiam@upmc.edu; 121 Meyran Ave. Rm 220; Pittsburgh PA 15213
What We Are Studying:
Behavior and brain function in response to computer tasks, pictures, peer interactions, and guessing tasks in young people.
Who Is Eligible to Participate:
Your adolescent may be eligible if: 1) he/she is between the ages of 14-18; 2) he/she does not have a history of mood or behavioral disorders and; 3) he/she has a same-sex, similar age friend willing to participate in a small task with them.
Who Is Not Eligible to Participate:
If your adolescent is a daily smoker, has a history of head trauma, or is currently taking psychiatric medications, they are not eligible to participate.
What Participation Involves:
Participants will be asked to complete interviews and questionnaires, computer tasks, and a brain imaging scan.
Do Participants Receive Compensation as Part of the Study:
Yes
What compensation Do Participants Receive:
Compensation is provided. The project coordinator can provide you with details.
Project Title:
ADAPT: Addressing Depression and Pain Together
Principal Investigator:
Jordan F. Karp, M.D.
For Information Contact:
Susan Mottu at mottuss@upmc.edu or 412-246-6006
What We Are Studying:
We know that low back pain and depression often make each other worse. Some patients notice an improvement in both low back pain and depression when they are treated with an antidepressant medication alone. However, for individuals who do not improve with an antidepressant medication that has also been observed to have anti-pain properties, we want to compare two treatments to see which is better. In this clinical trial, we are testing whether increasing the dose of medication along with supportive care or increasing the dose of medication and adding Problem Solving Therapy specific for managing the problems of low back pain and depression is the more effective treatment.
Who Is Eligible to Participate:
Men and women aged 60 or older who are experiencing both chronic low back pain and depression.
Who Is Not Eligible to Participate:
Individuals who are wheelchair-bound or are unable to tolerate the study medication.
What Participation Involves:
Depending on a participant's response, the study lasts between 6 and 20 weeks. During the first 6 weeks, participants receive a medication called venlafaxine (Effexor) and supportive care. Those participants who do not improve will be randomly assigned to one of two groups. One group receives higher-dose venlafaxine with continuing supportive care. The other group receives higher-dose venlafaxine with a counseling intervention called Problem Solving Therapy for Depression and Pain.
Do Participants Receive Compensation as Part of the Study:
Yes
What compensation Do Participants Receive:
To compensate participants for their time and travel, those who complete the first 6 weeks receive $60. Those who complete the second 14 weeks of the study receive another $60. Those participants who agree to one blood draw will be compensated another $10 (for a potential of $130).
Project Title:
Effects of an Active Medication (Olanzapine) versus an Inactive Medication (Placebo) in the Treatment of Outpatients with Eating Disorders (Anorexia Nervosa)
Principal Investigator:
Marsha Marcus, Ph.D.
For Information Contact:
Marcela Marin Dapelo at marindapeloma@upmc.edu or 412-246-5930
What We Are Studying:
We are examining the effectiveness of a research medication (olanzapine) in the outpatient treatment of adults with anorexia nervosa.
Who Is Eligible to Participate:
Women and men who are 18-55 years of age and have anorexia nervosa are eligible for consideration for the study.
Who Is Not Eligible to Participate:
Individuals receiving treatment for alcohol or drug dependence and pregnant women are not eligible for this study. In addition, individuals with anorexia nervosa who are unable to attend treatment in Pittsburgh are ineligible for consideration for the study.
What Participation Involves:
Prospective participants will complete a diagnostic interview, screening questionnaires, and a thorough medical evaluation before being accepted into the study. Individuals who qualify for the study will receive 16 weeks of medication (olanzapine or placebo), as well as medical management and support from a psychiatrist. In addition, enrolled participants will complete research assessments once per month during the intervention and 1 and 2 months after the intervention is completed.
Do Participants Receive Compensation as Part of the Study:
Yes
What compensation Do Participants Receive:
Enrolled participants can earn up to $250 by completing research assessment throughout the treatment, and at 1- and 2-month follow-up appointments. There is no compensation for the screening procedures or for attending treatment.
Project Title:
Perseverative Problem Solving Study (PPS)
Principal Investigator:
Neil Jones, PhD
For Information Contact:
Jillian Rodgers, rodgersj2@upmc.edu, 412.383.8143
What We Are Studying:
This study examines how the brain functions when individuals try to solve personally pressing problems.
Who Is Eligible to Participate:
Individuals ages 18-55 years old that are currently depressed and are not currently taking antidepressants and are not in any form of therapy. Individuals must have no history of head trauma/neurological disorder, no metal devices in their body, and no substance abuse or dependence in the past 3 months. Women who are not pregnant or planning to become pregnant may be eligible.
Who Is Not Eligible to Participate:
Individuals outside of the ages of 18-55 years old who are not currently depressed or who are currently taking antidepressants or engaged in any form of therapy. Individuals with a history of head trauma/neurological disorder, who have metal devices in their body, have experienced substance abuse or dependence in the past 3 months, and women who are pregnant or planning to become pregnant are not eligible.
What Participation Involves:
Over two visits, individuals will complete screening procedures, a clinical interview, questionnaires and engage in problem solving tasks during an fMRI brain scan.
Do Participants Receive Compensation as Part of the Study:
Yes
What compensation Do Participants Receive:
Subjects will receive up to $50 for the first assessment and up to $70 for the second assessment.
Project Title:
Autism Study
Principal Investigator:
Kirsten M. O'Hearn, Ph.D.
For Information Contact:
Brain Study Hotline at 412-383-8180 or lunalncd@gmail.com
What We Are Studying:
This study investigates how people interpret the visual world, and how these interpretations may differ in individuals with Autism Spectrum Disorders (ASD). In particular, we are interested in how the ability to effectively do visual tasks - like recognizing a friend or predicting an action - continues to improve through childhood and adolescence. This development of visual processing differs in ASD, and our current studies are examining what visual processes are affected, including differences in how the brain matures.
Who Is Eligible to Participate:
Adults and children ages 7-35 with OR without Autism may be eligible to participate.
Who Is Not Eligible to Participate:
Exclusions may apply.
What Participation Involves:
Participants of this study are asked to do a series of computer games, paper/pencil tests, and an MRI scan.
Do Participants Receive Compensation as Part of the Study:
Yes
What compensation Do Participants Receive:
Participants will be compensated $50-75 for each session of their involvement.
Project Title:
CHARTS: Children with Hyperactivity & Autism Research Treatment Study
Principal Investigator:
Benjamin Handen, Ph.D.
For Information Contact:
Sarah McAuliffe-Bellin, M.Ed., mcauliffebellinsj@upmc.edu; 412-235-5447
What We Are Studying:
The use of atomoxetine (Strattera) and parent training versus placebo for symptoms of ADHD in children with Autism Spectrum Disorder.
Who Is Eligible to Participate:
The following individuals may be eligible to participate: Children between 5-14 years of age; Symptoms or diagnosis of Autistic Disorder, Asperger’s Disorder or Pervasive Developmental Disorder; Symptoms of over-activity, inattention, impulsivity or diagnosis of ADHD; Children who are not on medication or are on medications that are not working well.
Who Is Not Eligible to Participate:
Individuals not meeting the eligibility criteria listed above.
What Participation Involves:
This study involves participation in 10 management sessions at the Merck Outpatient Clinic including initial screening visit. Sessions utilize various assessment tools to track safety and effectiveness of the intervention.
Do Participants Receive Compensation as Part of the Study:
Yes
What compensation Do Participants Receive:
Evaluations, study visits, parent training and medication are provided free of charge. An optional 24-week follow-up will be offered to all participants. Information on stipends can be obtained by contacting the Study Coordinator.
Project Title:
Mismatch Negativity and Complex Second-Order Sensory Memory in Schizophrenia
Principal Investigator:
Dean Salisbury, PhD
For Information Contact:
Kevin Eklund, RN, BSN, Email: eklundkd@upmc.edu, Telephone: (412) 586-9009
What We Are Studying:
This study seeks to understand more about auditory perceptual and memory problems in psychosis by studying (1) individuals who have just developed symptoms for the first time and have little or no treatment for the symptoms, (2) those with chronic schizophrenia, and (3) healthy individuals with no mental health problems.
Who Is Eligible to Participate:
Males and Females, Ages 18-55, who either: (1) have received treatment for the first time in the past 2 months for psychosis; (2) have a diagnosis of schizophrenia AND have had at least 3 hospitalizations for psychosis; or (3) healthy individuals with no history of mental health problems.
Who Is Not Eligible to Participate:
Those with a history of a diagnosed learning disorder, previous treatment for childhood ADHD, neurological disorder (like seizures) or severe head injury, drug/alcohol dependence. Certain medical illnesses may also exclude individuals from participating.
What Participation Involves:
A screening interview will determine eligibility. Those eligible will complete an EEG session, in which they will hear series of different sounds while watching a silent movie and having their brainwaves recorded to measure sensory memory. Participants will also complete clinical interviews and neuropsychological testing. Approximate time to completion can be up to 10 hours.
Do Participants Receive Compensation as Part of the Study:
Yes
What compensation Do Participants Receive:
Individuals may receive up to $150 for successful completion of the study.
Project Title:
Relationship Quality, Sleep, and Cardiovascular Risk in Military Couples
Principal Investigator:
Wendy Troxel, Ph.D.
For Information Contact:
Tyler Conrad (Email: conradt@upmc.edu; Telephone: 412-246-5783) Jodi Martin (Email: sausjl@upmc.edu; Telephone: 412-246-6965)
What We Are Studying:
The purpose of the study is to understand the connection between sleep and how couples function in their relationships, and how these processes may influence cardiovascular risk factors in military families.
Who Is Eligible to Participate:
1) Male or female Operation Iraqi Freedom (OIF) or Operation Enduring Freedom (OEF) or Operation New Dawn (OND) returnees and their spouses; 2) Between the ages of 18 and 45 years old; 3) Heterosexual Married or couples cohabiting for at least 1 years and 4) Currently sleeping together (>4 days/week).
Who Is Not Eligible to Participate:
Individuals taking medications or otherwise currently being treated for existing CVD (including hypertension, high-cholesterol) use of insulin or oral medications for diabetes. Individuals that use continuous positive airway pressure (CPAP) for sleep apnea or with severe, untreated sleep apnea (as defined by AHI <16 using portable apnea screening device). Women who are pregnant or breast feeding or Couples caring for a child under the age of 6 months.
What Participation Involves:
STEP 1: You will meet with a study staff member and go over the study in detail, and will begin to complete study-related interviews and questionnaires. You will go home with an in-home apnea screening device for you to use overnight which will assess for any sleep disorders. You will then individually visit our offices to meet with a study clinician. Each of these visits will take approximately 3 hours to complete. STEP 2: Over a 10-day period, we will ask you to wear a watch that will record your activity level, as well as provide you with a Palm Pilot to record daily events. On night 1 and night 2 study staff will arrive in your home to deliver and set up sleep monitoring equipment. On night 2, we will also provide you with supplies to collect overnight urine samples. At a convenient time between nights 3 and 10, you will wear a blood pressure monitor for 48 consecutive hours. The blood pressure monitors are portable devices which can be hidden under clothing. STEP 3: You will be asked to come back to our offices in the morning to provide a fasting blood draw, and you will be asked to engage in 2 videotaped discussions with your partner. This visit will last approximately 3 hours.
Do Participants Receive Compensation as Part of the Study:
Yes
What compensation Do Participants Receive:
Participants are eligible for up to $400 in total compensation for completing all aspects of the project.
Project Title:
The Effect of Exercise on Acute Nicotine Withdrawal
Principal Investigator:
Isabella Soreca, M.D.
For Information Contact:
Alison Richardson, 412-246-5911, smokingstudy@upmc.edu
What We Are Studying:
We are studying the effect of exercise on nicotine withdrawal symptoms.
Who Is Eligible to Participate:
Men and women between the ages of 18 and 39 who smoke at least 10 cigarettes per day and do not exercise regularly may be eligible.
Who Is Not Eligible to Participate:
Non-smokers, those who regularly exercise, and those younger than 18 or older than 39 years old.
What Participation Involves:
In order to determine whether you are eligible for this study, you must complete a medical evaluation including drug testing and blood tests, a psychiatric evaluation, and an overnight sleep assessment. Those who are eligible will then be invited to begin the study. As part of the study, you would be required to sleep overnight in the research lab for a total of 10 nights. You would also be required to completely abstain from smoking for 3 days on 3 different occasions. During your time in the study, you would be allowed to leave the lab each morning a few hours after you wake up, and would be required to return to the lab each evening 5 hours before bedtime. Your overnight stays may be scheduled several weeks apart, so it may take as long as 12 weeks to complete the entire study.
Do Participants Receive Compensation as Part of the Study:
Yes
What compensation Do Participants Receive:
Participants will receive $1225 if they complete the study. Participants who do not complete the study will be compensated according to the number of study visits completed.
Project Title:
Brain Imaging and Information Processing in Psychosis
Principal Investigator:
Raymond Cho, M.D.
For Information Contact:
Kevin Eklund, RN, BSN; eklundkd@upmc.edu; (412) 586-9009
What We Are Studying:
We are trying to learn about the causes of psychotic symptoms and are addressing this problem in a number of ways using recently developed methods of studying the structure and functioning of the brain and thinking processes that we believe may be involved. The purpose of this study is to better understand which aspects of brain functioning are affected in psychotic illnesses and whether this changes over time.
Who Is Eligible to Participate:
Males and Females, Ages 12-50: (1) first-episode of psychosis with little/no previous treatment, and (2) healthy controls with no history of a psychiatric disorder.
Who Is Not Eligible to Participate:
Those with certain medical/neurological conditions, mental retardation, pregnant women, substance use disorder in the previous month (for abuse) or six months (for dependence). Further, healthy controls who have a history of neuroleptic treatment or with a first-degree family history of psychosis are not eligible.
What Participation Involves:
Participants will be asked to complete interviews, urine drug screen, neuropsychological assessments and brain imaging methods that include Electroencephalography (EEG) and functional magnetic resonance imaging (fMRI). Certain assessments will be repeated after 8 weeks, 6 months and 1 year.
Do Participants Receive Compensation as Part of the Study:
Yes
What compensation Do Participants Receive:
Participants receive up to $195 at baseline and the 8-week follow-up, $100 at the 6-month follow-up and $125 at the 1-year follow-up.
Project Title:
STOP PD II (Sustaining Remission of Severe Depression II)
Principal Investigator:
Ellen Whyte, MD
For Information Contact:
Joelle Scanlon, PhD; Email: scanjm2@upmc.edu; Telephone: 412-246-6012
What We Are Studying:
Most of us have heard of depression, but few people may know about a type of depression that appears along with psychosis (or a loss of touch with reality). Referred to as psychotic major depression (PMD), it’s a surprisingly common mental disorder that affects more than one in 100 individuals. Researchers know that combination treatment (using both an antipsychotic + antidepressant) is needed when using medication to treat severe depression with psychosis. Now, researchers are working to understand how long people need to stay on an antipsychotic medication to prevent new episodes of psychosis after recovering from their initial symptoms.
Who Is Eligible to Participate:
Individuals, ages 18 to 85 years old, who experience the following symptoms: Persistently sad mood, feelings of hopelessness/pessimism, irritability/restlessness, poor sleep, feelings of guilt or worthlessness, poor concentration or memory problems, fatigue or poor energy, thoughts of suicide or suicide attempts, severe, distressing worries, hearing/seeing things that are bizarre or improbable, ideas or ways of thinking that are not true. Participation can begin in an inpatient or outpatient setting.
Who Is Not Eligible to Participate:
Individuals with current/lifetime DSM-IV defined psychotic disorder (e.g., schizophrenia, schizoaffective disorder, delusional disorder), Bipolar disorder, current DSM-IV defined OCD or Body Dysmorphic Disorder, DSM-IV defined substance abuse/dependence within the last 3 months, current diagnosis of dementia/significant premorbid cognitive impairment, Type I diabetes Mellitus, Pregnancy or plan to become pregnant, Medical instability
What Participation Involves:
First, participants will undergo a complete psychiatric and medical assessment, including a physical exam and blood tests, to make sure that the study medications are appropriate and safe for the individual. Individuals who are eligible to participate in Phase I will receive a combination of an antidepressant (Zoloft) and an antipsychotic (Zyprexa) for up to 20 weeks. If the participant responds to these medications, he/she will have the option of entering Phase 2, during which the participant will either continue with Zoloft + Zyprexa, or receive Zoloft + Placebo, for up to 36 weeks. The participant’s mood and overall health will be assessed frequently throughout the study. Study participants receive medication and medical care at no cost.
Do Participants Receive Compensation as Part of the Study:
Yes
What compensation Do Participants Receive:
$10 for Phase 1 research visits, $20 for Phase 2 research visits, Assistance with transportation if needed.
Project Title:
Investigation of Reduced Flushing in Patients with Schizophrenia (VA Merit Review Project)
Principal Investigator:
Jeffrey Yao, Ph.D., FACB
For Information Contact:
Jesse Conlon, Jesse.Conlon@va.gov, Telephone: 412-954-5787
What We Are Studying:
Niacin sensitivity and it?s relation to Schizophrenia.
Who Is Eligible to Participate:
Individuals aged 18-65 years old that have been diagnosed as Schizophrenia or Bipolar Disorder. The project is also recruiting people aged 18-65 years old that are in good health. Additionally, all participants must not be using from painkillers or high blood pressure medication, or have been diagnosed with problems involving peripheral blood circulation.
Who Is Not Eligible to Participate:
Subjects with family history of schizophrenia or bipolar disorders, those outside of the 18-65 age range, individuals taking painkillers or high blood pressure medication on a daily basis, those with mental retardation or pervasive developmental disorder, substance dependence within 6-months and/or substance abuse within a month, significant head injury, Lupus, peripheral vascular disorder, significant neurological disorder (such as Alzheimer?s disease, Parkinson disease or multiple sclerosis), pregnancy, and lack of capacity to understand study.
What Participation Involves:
Consenting to participate in the research study, performing a saliva drug-screen test, taking the Niacin Test, completing a questionnaire, and a blood draw.
Do Participants Receive Compensation as Part of the Study:
Yes
What compensation Do Participants Receive:
Participants will receive $20.00 at baseline for informed consent, saliva drug test, and niacin test, and $30 at one-time follow-up for niacin test (if applicable), questionnaire, questionnaire and blood draw.
Project Title:
Study of Interpersonal and Social Rhythm Therapy for Subthreshold Bipolar (BPNOS)
Principal Investigator:
Holly Swartz, MD
For Information Contact:
Joan Buttenfield; Email: buttenfieldja@upmc.edu; Telephone: 412-246-5588
What We Are Studying:
We are conducting research to understand whether an experimental talk therapy is effective in patients with Bipolar Disorder Not Otherwise Specified (BP-NOS) who are currently feeling depressed or down. Individuals who have BP-NOS may experience the "high" and "low" symptoms of bipolar disorder, but do not experience these symptoms long enough or severe enough to meet diagnostic criteria for bipolar disorder. However, the symptoms are clearly out of the person's normal range of behavior and may negatively affect everyday life.
Who Is Eligible to Participate:
Men and women, ages 18-65, who are currently feeling down but have had times where they felt overly energetic, and are interested in receiving talk therapy may be eligible to participate.
Who Is Not Eligible to Participate:
Individuals with severe medical disorders, psychosis, bipolar I disorder, primary obsessive compulsive disorder or eating disorder, borderline personality disorder or antisocial personality disorder, and those who are actively suicidal are not eligible to participate.
What Participation Involves:
Individuals who participate in this research study will receive 20 weeks of the psychotherapy Interpersonal and Social Rhythm therapy (IPSRT). Each IPSRT session lasts approximately one hour and is conducted by a trained clinician. Patients will receive a psychiatric evaluation, medical evaluation that may include a physical examination, laboratory tests and visits with a study psychotherapist and psychiatrist at no cost.
Do Participants Receive Compensation as Part of the Study:
Yes
What compensation Do Participants Receive:
Participants may be compensated up to $180 for full participation. Parking/bus fare is provided by the study. Food vouchers may also be provided for UPMC dining services during other lengthy research appointments.
Project Title:
Validating Early Human Screening of Cessation Medications
Principal Investigator:
Kenneth A. Perkins, Ph.D.
For Information Contact:
http://www.smokingstudies.Pitt.edu; Joshua Karelitz, karelitzjl@upmc.edu, 412-246-5306.
What We Are Studying:
We are examining the short-term effects of medications (versus placebo) in helping smokers to stop smoking during simulated quit attempts. The current medications of interest are bupropion and modafinil. Note that this study is not a quit smoking clinical trial, but some help with quitting is offered after the end of study participation (see below).
Who Is Eligible to Participate:
Healthy smokers ages 18-65 who are already planning on quitting smoking.
Who Is Not Eligible to Participate:
Those with major medical or psychiatric illnesses, women who are pregnant, planning to become pregnant, or breastfeeding.
What Participation Involves:
After the informed consent and physical exam sessions (totaling about 2 hrs), participants engage in three 3-week phases (9 weeks total). Each 3-week phase involves visits to the Oakland lab every other day (e.g. M, W, F) for the first two weeks and daily (M-F) during the third week. Participants will take bupropion, modafinil or a placebo daily for 2 weeks of each phase and will try to quit smoking for the last week of each phase.
Do Participants Receive Compensation as Part of the Study:
Yes
What compensation Do Participants Receive:
Participants completing all required sessions over the 9-week study will receive up to $845.
Project Title:
The Feel My Best Study: Reducing Depressive Symptoms in Systemic Lupus Erythematosus (SLE)
Principal Investigator:
Carol Greco, Ph.D.
For Information Contact:
Please contact Chris McFarland for more information at mcfarlandce@upmc.edu or by calling 412-623-6872.
What We Are Studying:
We are studying how two forms of counseling influence depressive symptoms in people with SLE and depression.
Who Is Eligible to Participate:
Adults over 18 years old who have systemic lupus, which is an autoimmune disease, and who also have symptoms of depression.
Who Is Not Eligible to Participate:
Persons with SLE whose medications are not stable for at least 1 month, or who are unwilling to suspend their current psychotherapy; persons who do not have SLE.
What Participation Involves:
Participants will be asked to complete a pre- and post-treatment medical and psychosocial evaluation, participate in counseling sessions, and take part in 6-month and 12-month follow-up evaluations. The counseling consists of 8 sessions of either Mind-Body Skills Training or Supportive Counseling. Three "booster" sessions of counseling are offered once each month for the three months following the counseling.
Do Participants Receive Compensation as Part of the Study:
Yes
What compensation Do Participants Receive:
Participants receive a total of $80 if they complete: all 8 counseling sessions ($20), the post-treatment evaluation ($20), the 6-month follow-up evaluation ($20) and the 12-month follow-up evaluation ($20)
Project Title:
MS Heart Study
Principal Investigator:
Rebecca Thurston, Ph.D.
For Information Contact:
Shannon Nichter: 412-642-2016 OR Melanie Heinricher: 412-648-7068; Email: msheartstudy@gmail.com
What We Are Studying:
The study is designed to better understand the development of cardiovascular risk in midlife women.
Who Is Eligible to Participate:
Healthy volunteers, women, non-smoking, no known cardiovascular disease, not taking hormones, cardiac medications, insulin or antidepressants. No history of hysterectomy or removal of ovaries. Women with no hot flashes or daily hot flashes may be eligible.
Who Is Not Eligible to Participate:
Men, women under age 40 or over age 60, currently smoking or using tobacco products, women who had had a hysterectomy or bilateral oophorectomy, or are currently pregnant. Women using taking hormones, antidepressants or undergoing chemotherapy currently or in the last three months. Women undergoing treatment for cardiovascular disease, using insulin for the treatment of diabetes, or with a history of stroke.
What Participation Involves:
Participation includes wearing monitors that measure heart rate, hot flashes, and sleep as you go about your daily activities. Study procedures also include ultrasound images of your blood vessels and one fasting blood draw.
Do Participants Receive Compensation as Part of the Study:
Yes
What compensation Do Participants Receive:
Participants are eligible to receive $150 compensation. Study also provides compensation for bus fares and parking fees for lab visits.
Project Title:
ADHD Study
Principal Investigator:
Katerina Velanova, Ph.D.
For Information Contact:
412-383-8171 or velanovak@upmc.edu
What We Are Studying:
This study looks at the ability of adolescents with and without ADHD to regulate their voluntary behaviors, and the brain mechanisms that support this kind of cognitive control. The purpose is to determine what parts of the brain are involved in ADHD, and how the function of these brain regions changes with the spontaneous improvements in ADHD symptoms that sometimes occur during adolescence.
Who Is Eligible to Participate:
Teens aged 13-17 with no history of psychiatric disorder or brain injury AND teens aged 13-17 who have been diagnosed with ADHD (regardless of whether they currently have ADHD) may be eligible to participate.
Who Is Not Eligible to Participate:
Teens taking medications for psychiatric conditions other than ADHD.
What Participation Involves:
Teens and their parents will be interviewed. Teen participants will also be asked to do a series of computer games and an MRI.
Do Participants Receive Compensation as Part of the Study:
Yes
What compensation Do Participants Receive:
Participants will be compensated $200 for completion of three study sessions.
Project Title:
Buprenorphine for Treatment Resistant Depression
Principal Investigator:
Jordan Karp, M.D.
For Information Contact:
Crystal Spotts, Program Coordinator, spottscr@upmc.edu, 412-246-6111
What We Are Studying:
Depression often does not respond to typical treatments such as antidepressants and therapy. People with treatment-resistant depression often suffer from chronic depression without relief. Though much is known about treating depression, innovative treatments are sorely needed. Research allows us to explore new ways to alleviate depression. A pilot study showed that a medication called buprenorphine has an anti-depressant effect. This study is a placebo-controlled 8 week trial of buprenorphine. Participants may receive placebo or buprenorphine during the study. Buprenorphine is an opioid medication. It comes in a pill form that melts under the tongue. We use it at a very low dose in this study, starting at 0.2 mg. After 8 weeks those who received placebo may enter an open-label trial (receive buprenorphine) for an additional 8 weeks. An MRI scan is done before and after the first dose of medication to detect changes in brain chemistry.
Who Is Eligible to Participate:
You may be eligible to participate if you are: 1) Over age 21; 2) Have tried at least 2 antidepressants for at least 6 weeks each; 3) Have current major depression and; 4) Able to undergo an MRI scan.
Who Is Not Eligible to Participate:
Some (not all) exclusion criteria include the following items: 1) Current opioid use or history of opioid dependence or abuse; 2) Substance use, dependency or abuse; 3) Hepatic impairment; 4) A diagnosis of dementia, bipolar disorder I or II, schizophrenia, schizoaffective disorder, schizophreniform disorder, delusional disorder or current psychotic disorder; 5) Inability to communicate in English and; 6) Unstable medical illness.
What Participation Involves:
People enrolled in this study: 1) Receive a comprehensive evaluation of your mental and physical health; 2) Attend brief weekly progress visits for 8-16 weeks and complete questionnaires; 3) Complete MRI scanning at the beginning of the study; 4) Take simple memory tests 3 times during the study and; 5) Take provided medication, at no cost to you.
Do Participants Receive Compensation as Part of the Study:
Yes
What compensation Do Participants Receive:
Participants are compensated $10 after completion of the fMRI scan.
Project Title:
Reward and Risk for Adolescent Depression
Principal Investigator:
Thomas Olino, Ph.D.
For Information Contact:
Catherine Venable, venablecm@upmc.edu, (412) 624-7991
What We Are Studying:
The purpose of this research study is to learn about factors that can contribute to or prevent teenagers from becoming depressed. Specifically, we are interested in the ways that children experience rewards and positive emotions. We hope to learn how reward and positive emotions are related to depression.
Who Is Eligible to Participate:
Parents, with and without a history of depression, who have at least one child between ages 10 and 16.
Who Is Not Eligible to Participate:
Parents who have a history of mania, bipolar disorder, or psychosis. Children are ineligible if they have been diagnosed with depression, mania, bipolar disorder, or psychosis.
What Participation Involves:
Participation involves parents and children completing interviews and questionnaires, children completing brief computer tasks, and children completing an fMRI scan. Parents and children will be asked to complete questionnaires 9- and 18-months after the initial sessions and parents and children will be asked to complete a second interview at the 18-month assessment.
Do Participants Receive Compensation as Part of the Study:
Yes
What compensation Do Participants Receive:
Compensation for your family's time will be given. Please contact the study coordinator for further details.
Project Title:
Comprehensive Examination of the Association Between Sleep and Suicidality in Youth with Bipolar Disorder
Principal Investigator:
Tina Goldstein, Ph.D.
For Information Contact:
Lindsay Kurahara; Email: kuraharals@upmc.edu; Telephone: 412-246-6064
What We Are Studying:
This study is looking at the connection between specific types of sleep issues, mood, thoughts, and behavior. Additionally, we are looking at participants’ reaction to stress and how their emotions are processed. We will compare the data of healthy controls to that of age-matched youth with bipolar disorder.
Who Is Eligible to Participate:
Healthy Control Inclusion Criteria: 1) Age 13 years to 22 years old; 2) Able to speak/read English at a 3rd grade level; 3) Able and willing to give informed consent/assent to participate.
Who Is Not Eligible to Participate:
Individuals are not eligible if: 1) there is evidence of mental retardation, pervasive developmental disorder (PDD), or organic central nervous system disorder; 2) they have a severe medical condition requiring immediate treatment; 3) they have a history of a mood disorder, anxiety disorder, or any current psychiatric diagnosis; 4) they have a first-degree relative with history of bipolar disorder; 5) they have a sleep disorder; 6) are currently taking any medications known to affect sleep and; 7) they have a sibling already enrolled in this study. Additional exclusion criteria for fMRI scan eligibility: 1) left-handed; 2) cannot be in small spaces (claustrophobic); 3) metal in their body or braces/permanent retainer; 4) body piercing that the participant is unable or unwilling to remove for the fMRI scan; 5) pregnant or planning to become pregnant during participation in the study; and 6) head injury with any loss of consciousness.
What Participation Involves:
For this study, participants will be asked to complete an interview, some questionnaires online, a sleep diary, computer tasks, and a functional magnetic resonance imaging (MRI) scan to look at brain activity. This research study does not involve any treatments or medications.
Do Participants Receive Compensation as Part of the Study:
Yes
What compensation Do Participants Receive:
There is compensation for participation in this study. You may contact the project coordinator for further details.
Project Title:
Perspectives Program
Principal Investigator:
Shaun Eack, Ph.D.
For Information Contact:
Amber Bahorik, autismrecruiter@upmc.edu or 1-866-647-3436; http://www.pittautismresearch.org
What We Are Studying:
These non-drug research interventions provide support for individuals with ASD and are designed to improve social functioning, problem-solving and stress management.
Who Is Eligible to Participate:
Individuals with High Functioning Autism, Asperger?s Syndrome or Pervasive Developmental Disorder NOS, ages 16-45.
Who Is Not Eligible to Participate:
Individuals with autism who have an IQ < 80. Individuals with suicidal/homicidal behavior and/or recent substance abuse.
What Participation Involves:
Eligible candidates will be treated with one of two new research interventions: Cognitive Enhancement Therapy is a treatment for improving thinking, planning and effectiveness in social situations. This research treatment approach is designed to improve attention, memory, and problem-solving skills, as well as social interactions with others. Enriched Supportive Therapy provides individual supportive therapy to help individuals with autism spectrum disorders learn about their condition, manage their emotions and stress, improve their social skills and cope with everyday problems. In addition to receiving the research interventions, participants will be asked to complete interviews, cognitive testing and diagnostic assessments.
Do Participants Receive Compensation as Part of the Study:
Yes
What compensation Do Participants Receive:
Total compensation can be up to $250, for completing all aspects of the program. An additional $100 is available for individuals completing in a voluntary MRI scan.
Project Title:
Pregnancy-Associated Sleep Disturbances May Increase Pregnancy Complications
Principal Investigator:
Michele Okun, Ph.D.
For Information Contact:
Bonnee Wettlaufer at wettlauferbe@upmc.edu or 412-246-6419
What We Are Studying:
There currently are scant published data linking disturbed sleep with pregnancy complications/outcomes. The goal of this research is to empirically examine the role of sleep disturbances and increased inflammation in the pathogenesis of pregnancy complications. This goal will be accomplished by examining: 1) the relationship between pregnancy-related sleep disturbances in the early gestational period and subsequent pregnancy complications; 2) the relationship between pregnancy-related sleep disturbances and inflammation during the first and second trimesters; and 3) examining if sleep-related increases in inflammation are associated with pregnancy complications.
Who Is Eligible to Participate:
Women are eligible if they are between 18-45 and no more than 14 weeks pregnant.
Who Is Not Eligible to Participate:
Anyone not a pregnant female.
What Participation Involves:
At the initial in-person meeting, written informed consent and permission to review obstetrical records will be obtained. Participants will complete a Sociodemographics and Health Behaviors questionnaire. Participants will be given an Actiwatch activity monitor and sleep diary along with detailed instructions on use of the equipment and diary for the following 14-day period. Prior to their return visit on Day 15, participants will be given a reminder call to begin fasting after midnight. Participants will return the Actiwatch and sleep diary. They will complete a battery of questionnaires on a computer. Following this a nurse will administer a general medical evaluation obtaining height, weight, blood pressure and medication use. Lastly, the nurse will obtain a fasting blood sample (2 Tablespoons). Women will return in 2 weeks to receive an Actiwatch and sleep diary to complete for 2 weeks. They will again return to WPIC on the 15th day of this phase to return the sleep diary and Actiwatch, complete questionnaires and provide a blood sample (~2 Tablespoons). Participants return a third time 2 weeks later to receive the Actiwatch and sleep diary to complete for 2 weeks for a third time. They will again return to WPIC on the 15th day of this phase to return the sleep diary and Actiwatch, complete questionnaires and provide a blood sample (~2 Tablespoons).
Do Participants Receive Compensation as Part of the Study:
Yes
What compensation Do Participants Receive:
$50 for the completion of each study timepoint. Total compensation is up to $150.
Project Title:
Early Assessment and Intervention for Adolescents at Risk for Bipolar Disorder
Principal Investigator:
Tina R. Goldstein, PhD
For Information Contact:
Reality Price; Email: pricerj@upmc.edu; Telephone: 412-864-3321
What We Are Studying:
Identifying and treating the children of parents with bipolar disorder may help prevent or slow the progression of bipolar disorder. Using experimental talk therapy, called Interpersonal and Social Rhythm Therapy (IPSRT) with a study therapist, we may help teens and their family members to better understand how people develop bipolar disorder, develop more regular sleep schedules that may protect against mood problems, recognize symptoms of bipolar disorder and decrease stress in family relationships
Who Is Eligible to Participate:
1) age between 12-18 years; 2) primary residence with a parent or guardian; 3) English language fluency and at minimum a 3rd grade literacy level. Subjects must be able to speak and understand English because one of the study interventions, Brief IPSRT, is an experimental talk-therapy. This therapy cannot practically be translated; 4) a biological parent with a diagnosis of Bipolar Disorder I, II or Not Otherwise Specified (NOS) confirmed via semi-structured diagnostic interview
Who Is Not Eligible to Participate:
1) a current or lifetime bipolar spectrum disorder diagnosis (i.e., Bipolar Disorder I, II or NOS) by the Schedule for Affective Disorders and Schizophrenia-Present and Lifetime Version (K-SADS-PL); 2) a primary sleep disorder diagnosis by the Structured Interview for DSM-IV Sleep Disorders; 3) current unstabilized psychiatric symptoms as evidenced by a CGI-Severity of > 5 (markedly ill) and/or a C-GAS rating of < 50 (denotes serious symptoms); 4) evidence of mental retardation, pervasive developmental disorder, or organic central nervous system disorder by the K-SADS-PL, parent report, medical history, or school records; 5) a prior course of IPSRT treatment
What Participation Involves:
In person visits at Bellefield Towers at intake, month 3 & 6, online assessments at 1.5 & 4.5 months, wearing an actiwatch to monitor sleep patterns at intake & 6 months, 5-8 IPSRT treatment sessions if randomized to the experimental talk therapy.
Do Participants Receive Compensation as Part of the Study:
Yes
What compensation Do Participants Receive:
$285 total for completion of all study visits and tasks; Travel reimbursement at intake, 3, 6 (bus tickets can also be provided for in person and IPSRT treatment sessions)
Project Title:
The Couples Study
Principal Investigator:
Paul Pilkonis, Ph.D.
For Information Contact:
Andrea Chavlovich, chavlovicha@upmc.edu 412-246-5832
What We Are Studying:
We are interested in the associations between personality traits, emotions, and how individuals interact with people close to them. We are also interested in the experience of being in a relationship with someone receiving mental health care.
Who Is Eligible to Participate:
Couples who are currently involved in a romantic relationship for at least a month may be eligible. One person in the couple must be currently receiving mental health treatment and be between the ages of 18 and 40 years old.
Who Is Not Eligible to Participate:
Individuals who are not currently in a romantic relationship, individuals who are not in the age range, and individuals with traumatic brain injuries, strokes, or other major problems of the central nervous system.
What Participation Involves:
Both members of the couple participate, but the information they provide is not shared between them. Participants will complete a series of questionnaires and interviews asking about their past and current mental health treatment; the nature and quality of their relationships with their romantic partner, family, and friends; and how they react in certain situations. Participants will also be asked to complete a computer task and to tell us about their day-to-day lives using smart phones. One task is completed with both people together – a discussion in our office. Some tasks are repeated at different times over a one-year period.
Do Participants Receive Compensation as Part of the Study:
Yes
What compensation Do Participants Receive:
Participants will each receive $25 to $50 for every visit, with maximum compensation that could amount to $775 per person over an entire year.
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