Complement Genes in Schizophrenia and Autoimmune Disease

Events

Complement Genes in Schizophrenia and Autoimmune Disease

Steve McCarroll, PhD Dorothy and Milton Flier Associate Professor of Biomedical Science and Genetics and Director of Genetics, Stanley Center for Psychiatric Department of Genetics, Harvard Medical School

The Department of Psychiatry kicks off its Fall 2018 Lecture Series with a special presentation by Steve McCarroll, PhD, Director of Genetics for the Stanley Center for Psychiatric Research at the Harvard Medical School. 

Steve McCarroll, PhDDr. McCarroll and the scientists in his lab work to identify the mechanisms by which genetic variation shapes human biology.   They seek to develop new ways to make sense of human genetic data and understand how genetic effects manifest in cells and tissues  His lab has uncovered surprising ways in which genes and alelles shape risk of human diseases – from schizophrenia (Sekar et al., Nature 2016) to cardiovascular illness (Boettger et al., Nature Genetics 2016) to cancer (Genovese et al., NEJM 2017).  Steve’s lab also developed Drop-seq, a widely adopted technology for studying RNA expression in complex tissues (such as the brain) at single-cell resolution

The entirety of this program will be a lecture by the speaker(s). All individuals able to control the content of this educational activity are required to disclose all relevant financial relationships with any proprietary entity producing, marketing, re-selling, or distributing health care goods or services, used on, or consumed by, patients. Registration is not required for this event. This event is free and there will be no refunds. The University of Pittsburgh is an affirmative action, equal opportunity institution.

Location: Western Psychiatric Institute and Clinic Auditorium

For More Information. Please contact Frances Patrick at patrickfm@upmc.edu or at 412-246-6787.

Learning Objectives. At the conclusion of this lecture participants will be able to:

  1. Understand the ebullient genetic variation that affects the complement component 4 genes in the human genome. 

  2. Describe how this genetic variation relates to risk of schizophrenia, and what this suggests about potential mechanisms

  3. Understand how this genetic variation relates to risk of autoimmune disease, and what this suggests about potential mechanisms

Continuing Education Credit:  The University of Pittsburgh School of Medicine is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians.  The University of Pittsburgh School of Medicine designates this educational activity for a maximum of 1.5 AMA PRA Category 1 CreditsTM.  Each physician should only claim credit commensurate with the extent of their participation in the activity.  Other health care professionals are awarded .15 continuing education units (CEUs), which are equal to 1.5 contact hours.  In accordance with Accreditation Council for Continuing Medical Education requirements on disclosure, information about relationships of presenters with commercial interests (if any) will be included in materials which will be distributed at the time of the conference. WPIC is approved by the American Psychological Association to offer continuing education for psychologists.  WPIC maintains responsibility for this program and its contents.  This program is being offered for 1.5 continuing education credits.
The indicated number of clock hours of continuing education is provided through Western Psychiatric Institute and Clinic of UPMC’s Office of Educational Resources and Planning, a PA-approved provider of social work continuing education in accordance with all the applicable educational and professional standards of the Pennsylvania State Board of Social Workers, Marriage and Family Therapist. These clock hours satisfy requirements for LSW/LCSW, LPC and LMFT renewal. For more information, call (412) 204-9085.