Education & Training
Selected Honors & Awards
- Logan, R.W., Arjona, A. and Sarkar, D.K. (2011). Role of sympathetic nervous system in the entrainment of circadian natural-killer cell function. Brain, Behavior, and Immunity. 25(1), 101-109. PMID: 20816749.
- Logan, R.W., Zhang, C., Murugan, S., OConnell S., Levitt, D., Rosenwasser A.M. and Sarkar D.K. (2012). Chronic shift-lag alters the circadian clock of natural killer cells and promotes lung cancer growth in rats. Journal of Immunology. 188(6), 2583-2591. PMID: 22308312
- Logan, R.W., Robledo, R.F., Recla, J.M., Philip, V.M., Jay, J.J., Harwood, C., Gatti, D.M., Bult, C.J., Churchill, G.A., and Chesler, E.J. (2013). High-precision genetic mapping of behavioral traits in the Diversity Outbred mouse population. Genes, Brain and Behavior. 12(4), 424-437. PMID: 23433259.
- Logan, R.W., Edgar, N., Gillman, A.G., Hoffman, D., Zhu, X. and McClung, C.A. (2015). Chronic stress induces brain region specific alterations in molecular rhythms in mice that correlate with depression-like behavior. Biological Psychiatry, 78(4), 249-258. PMID: 25771506.
- Chen, C., Logan, R.W., Ma, T., Tseng, G.C., Sibille, E., and McClung, C.A. (2015). The effects of aging on circadian patterns of gene expression in the human prefrontal cortex. Proceedings of the National Academy of Sciences, Epub ahead of print. PMID: 26699485.
Department Faculty Highlight the Role of Adolescent Sleep and Circadian Rhythm Disruptions in Risk of Substance Use Disorders
Sleep and circadian rhythms, the 24-hour cycles of the body’s physiological processes, are important components of health. Likewise, disruptions in these systems are linked to a number of health conditions, including substance abuse. The developmental changes in sleep and circadian rhythms that occur during adolescence leave teenagers particularly vulnerable to addiction. A review recently published in the journal...
Translational Neuroscience Program Faculty Show Circadian Rhythms Regulate Reward through Metabolic Signaling in the Brain
Circadian rhythms are near 24-hour oscillations controlling many aspects of physiology and behavior. The coordination and orchestration of these rhythms maintain homeostasis throughout the body. Evidence from humans suggests disruptions to circadian rhythms and sleep are linked to several psychiatric disorders, including substance use and abuse disorders. Indeed, several human and animal studies have demonstrated...
Findings by Dr. Marianne Seney et al. Show Opposite Brain Transcriptional Profiles in Men and Women with Major Depressive Disorder
Major depressive disorder (MDD) is a devastating psychiatric disorder and leading cause of disability worldwide. It affects women approximately twice as often as men, and incidence and symptoms differ between the sexes, affirming the importance of studying brain pathology of depression in both men and women. Women are three times as likely to have atypical depression, with hypersomnia and weight gain, suggesting...
Hot Publication - Logan et al.
Chronic Stress Induces Brain Region-Specific Alterations of Molecular Rhythms that Correlate with Depression-like Behavior in MiceLogan RW, Edgar N, Gillman AG, Hoffman D, Zhu X and McClung CA Biological Psychiatry, 78:249-258, 2015 Emerging evidence implicates circadian abnormalities as a component of the pathophysiology of major depressive disorder (MDD). The suprachiasmatic nucleus (SCN) of the hypothalamus...