Michele A Bertocci, PhD
Education & Training
- Bertocci MA, Hanford L, Manelis A, Iyengar S, Youngstrom E, Gill MK, Monk K, Versace A, Bonar L, Bebko G, Ladouceur CD, Perlman SB, Diler R, Horwitz S, Arnold E, Hafeman D, Travis M, Kowatch R, Holland SK, Fristad M, Findling R, Birmaher B, Phillips ML. (in press) Clinical, cortical thickness, and neural activity predictors of future affective lability in youth at risk for bipolar disorder: initial discovery and independent sample replication. Molecular Psychiatry
- Soehner AM, Bertocci MA, Levenson JC, Goldstein TR, Diler R, Axelson D, Goldstein BI, Brent DA, Hickey MB, Monk K, Sakolsky D, Birmaher B, Phillips ML. Longitudinal associations between sleep patterns and psychiatric symptom severity in high-risk and community comparison youth. JAACAP, In Press
- Bertocci MA, Bebko G, Iyengar S, Dwojak A, Bonar L, Versace A, Forbes EE, Fournier J, Almeida JR, Perlman SB, Schirda C, Travis M, Gill MK, Diwadkar VA, Forbes E, Sunshine JL, Holland SK, Kowatch RA, Birmaher B, Axelson D, Horwitz SM, Frazier TW, Arnold LE, Fristad MA, Youngstrom EA, Findling RL, Phillips ML. (2017) Reward-Related Neural Activity Predicts Future Real-World Risky Substance Use Behaviors in Dysregulated Youth. Psychological Medicine 47(8):1357-69.
- Greenberg T, Bertocci MA, Chase HW, Fournier JC, Aslam H, Stiffler R, Lockovich J, Graur S, Bebko GM, Forbes EE, Phillips ML. (2017) Predicting quality of life from neural reactivity and anxiety a mediation model. Translational Psychiatry 7(7):e1178
- Bertocci MA, Bebko G, Dwojak A, Iyengar S, Ladouceur CD, Versace A, Fournier J, Bonar L, Almeida JR, Perlman SB, Schirda C, Travis M, Gill MK, Diwadkar VA, Forbes E, Sunshine JL, Holland SK, Kowatch RA, Birmaher B, Axelson D, Horwitz SM, Frazier TW, Arnold LE, Fristad MA, Youngstrom EA, Findling RL, Phillips ML. (2017) Longitudinal relationships among activity in neural circuitry underlying redirection of attention during emotional regulation and symptom severity in youth. Biological Psychiatry: CNNI 2(4):336-45.
Now in Journal of the American Academy of Child & Adolescent Psychiatry: Sleep Disturbances & Increasing Psychiatric Symptoms in High-Risk Youth
Major psychiatric disorders often arise during childhood and adolescence, especially among children whose parents have a psychiatric illness. Sleep patterns also shift substantially during the transition from childhood to adolescence. Sleep disturbances, often associated with most forms of psychopathology, have been identified as a promising behavioral intervention target to help treat young people with psychiatric...
Bertocci et al. Use Machine Learning to Identify Neuroimaging Markers that Predict the Development of Bipolar Disorder Symptoms in High-Risk Children
Bipolar disorder (BD) is a highly heritable mental illness in which affected individuals experience alternating periods of mania and depression. For more than 15 years, Pitt Department of Psychiatry researchers have been conducting longitudinal assessments of families with BD aimed at identifying the earliest signs of the disorder. The latest analysis of this neuroimaging data, recently published in the journal...
Department of Psychiatry Researchers Study How Trauma-affected Connectivity During Reward Learning Predicts Anxiety & Depression in Young Adults
When children and adolescents experience trauma, they are at risk for depression and anxiety. One way that this can occur is through trauma-induced impairment of the ventral striatum, a key region of the brain associated with reward learning. Impaired reward processing is associated with depression and anxiety in adolescence and adulthood, and young people with depression experience abnormally low ventral striatum...
Phillips and Colleagues Find New Risk Marker of Bipolar Disorder in Most Comprehensive Neuroimaging Study of High-Risk Children to Date
Mary Phillips, MD, MD (CANTAB), left, pictured with the publication's lead author, Heather Acuff. Bipolar disorder (BD), formerly known as manic depression, is a serious mental illness characterized by extreme changes in mood and energy levels that cycle between mania and depression. BD is highly heritable, so children of individuals with BD have an increased risk of also developing the disorder, which often first...