Faculty

Leonardo D'Aiuto, PhD

Research Instructor in Psychiatry

Contact Details

3811 O'Hara St.
Pittsburgh
 
PA
 
15213
Assistant
Beth Wesesky

Education & Training

PhD
University of Bari, Italy Molecular Genetics and Evolution
University of PittsburghEpigenetics and Stem Cell Biology
University of EdinburghHuman Genetics

Research Interests

Modeling of CNS infections using induced pluripote; Modeling schizophrenia using induced pluripotents; Development of three-dimensional neuronal platform
Selected Research Publications & Products
  1. D'Aiuto L, Williamson K, Dimitrion P, McNulty J, Brown CE, Dokuburra CB, Nielsen AJ, Lin WJ, Piazza P, Schurdak ME, Wood J, Yolken RH, Kinchington PR, Bloom DC, Nimgaonkar VL. Comparison of three cell-based drug screening platforms for HSV-1 infection. Antiviral Res. 2017 Jun;142:136-140.
  2. McNulty J, D'Aiuto L, Zhi Y, McClain L, Zepeda-Velzquez C, Ler S, Jenkins HA, Yee MB, Piazza P, Yolken RH, Kinchington PR, Nimgaonkar VL. iPSC Neuronal Assay Identifies Amaryllidaceae Pharmacophore with Multiple Effects against Herpesvirus Infections. ACS Med Chem Lett. 2015 Nov 19;7(1):46-50.
  3. McClain L, Zhi Y, Cheng H, Ghosh A, Piazza P, Yee MB, Kumar S, Milosevic J, Bloom DC, Arav-Boger R, Kinchington PR, Yolken R, Nimgaonkar V, D'Aiuto L. Broad-spectrum non-nucleoside inhibitors of human herpesviruses Antiviral Res. 2015 Sep;121:16-23.
  4. D'Aiuto L, Prasad KM, Upton CH, Viggiano L, Milosevic J, Raimondi G, McClain L, Chowdari K, Tischfield J, Sheldon M, Moore JC, Yolken RH, Kinchington PR, Nimgaonkar VL. Persistent infection by HSV-1 is associated with changes in functional architecture of iPSC-derived neurons and brain activation patterns underlying working memory performance. Schizophr Bull. 2015 Jan;41(1):123-32.
  5. D'Aiuto L, Di Maio R, Heath B, Raimondi G, Milosevic J, Watson AM, Bamne M, Parks WT, Yang L, Lin B, Miki T, Mich-Basso JD, Arav-Boger R, Sibille E, Sabunciyan S, Yolken R, Nimgaonkar V. Human induced pluripotent stem cell-derived models to investigate human cytomegalovirus infection in neural cells. PLoS One. 2012;7(11):e49700.

Education Interests

Teaching stem cell-based technologies; Molecular genetics training; Mentorship of early-career researchers