Howard J Aizenstein, MD, PhD
Education & Training
Selected Honors & Awards
- Karim, H. T., et al. \Intrinsic functional connectivity in late-life depression: trajectories over the course of pharmacotherapy in remitters and non-remitters.\" Molecular psychiatry 22.3 (2017): 450."
- Lim HK, Nebes R, Snitz B, Cohen A, Mathis C, Price J, Weissfeld L, Klunk W & Aizenstein HJ. (2014) Regional amyloid burden and intrinsic connectivity networks in cognitively normal elderly subjects. Brain. 137: 3327-3338. PMCID: PMC4240287
- Aizenstein HJ, Andreescu C, Edelman KL, Cochran JL, Price J, Butters MA, Karp J, Patel M, & Reynolds CF 3rd. (2011) fMRI correlates of white matter hyperintensities in late-life depression. The American Journal of Psychiatry. 168(10):1075-82. PMCID: PMC3656408
- Aizenstein HJ, Nebes RD, Saxton JA, Price JC, Mathis CA, Tsopelas ND, Ziolko S, James JA, Snitz B, Houck P, Bi W, Cohen A, Lopresti BJ, DeKosky ST, Halligan E, & Klunk WE. (2008) Frequent amyloid deposition without significant cognitive impairment among the elderly. Archives of Neurology. 65(11):1509-17. PMCID: PMC2636844
- Aizenstein HJ, Butters MA, Figurski JL, Meltzer CC, Stenger VA, Reynolds CF 3rd, Carter CS. (2004) Prefrontal and striatal activation during sequence learning in geriatric depression. Presented at the Society for Neuroscience Annual Meeting, San Diego, CA.
Investigators in the Geriatric Psychiatry Neuroimaging Lab Publish First Study to Explore Cerebral Blood Flow Correlates of Worry Induction in Late Life
Published in Translational Psychiatry Severe worry arises from a complex blend of maladaptive affective and cognitive processes. Contrary to other forms of anxiety, there is no consensus in the field regarding the neural basis of worry. No previous study has looked at cerebral blood flow changes associated specifically with in-scanner induction and reappraisal of worry. In the first study of its kind, Department of...
Department Faculty Members and Student Researcher Receive ACNP Travel Awards
The American College of Neuropsychopharmacology (ACNP) selected three faculty members (Drs. Jay Fournier , Danella Hafeman and Judith Morgan ) and a Medical Scientist Training Program (MSTP) student (Dr. Wonjae Chung) in the Department of Psychiatry to receive travel awards. ACNP annually selects distinguished young scientists in the field of neuropsychopharmacology to receive these awards, which offer an...
Hot Publication - Buysse & Colleagues
Sleep-Wake differences in relative regional cerebral metabolic rate for glucose among patients with insomnia compared with good sleepers Kay DB, Karim HT, Soehner AM, Hasler BP, Wilckens KA, James JA, Aizenstein HJ, Price JC, Rosario BL, Kupfer DJ, Germain A, Hall MH, Franzen PL, Nofzinger EA and Buysse DJ SLEEP 2016, 39:1779-1794 The neurobiological mechanisms of insomnia may involve altered patterns of activation...
Hot Publication - Karim et al.
Intrinsic functional connectivity in late-life depression: Trajectories over the course of pharmacotherapy in remitters and non-remitters Karim HT, Andreescu C, Tudorascu D, Smagula SF, Butters MA, Karp JF, Reynolds C and Aizenstein HJ Molecular Psychiatry, Published online 2016 Previous studies in late-life depression (LLD) have found that patients have altered intrinsic functional connectivity in the dorsal...